Table 3.

Longitudinal association between LE8 score (5-unit decrements), CV health, and LE8 components with HDP during a pregnancy, CARDIA study 1985-2015 (n=2036 births)

	Model 1	Model 2
	OR (95% CI)	OR (95% CI)
LE8 OVERALL SCORE	1.16 (1.06, 1.26)*	1.18 (1.07, 1.30)*
Per 5-unit decrement
LE8 COMPONENT SCORE
Per 10-unit decrement
Diet	0.98 (0.92, 1.05)	0.99 (0.92, 1.06)
Physical Activity	0.97 (0.91, 1.03)	1.00 (0.94, 1.07)
Nicotine Exposure	1.03 (0.98, 1.09)	1.03 (0.97, 1.08)
Sleep	1.08 (0.98, 1.20)	1.09 (1.00, 1.20)
Body Mass Index	1.17 (1.10, 1.25)*	1.18 (1.11, 1.27)*
Blood Glucose	1.13 (0.99, 1.29)	1.21 (1.06, 1.39)*
Blood Lipids	1.09 (1.01, 1.18)*	1.10 (1.02, 1.19)*
Blood Pressure	1.21 (1.09, 1.34)*	1.31 (1.17, 1.46)*
†CV HEALTH
High	Ref	Ref
Moderate	1.74 (1.13, 2.69)*	1.78 (1.13, 2.81)*
Low	3.37 (0.98, 11.61)	3.95 (1.05, 14.88)*

^*p<0.05

^†CV health defined based on overall LE8 score (low: LE8 score <50, moderate: LE8 score 50-79), high: LE8 score ≥80)

Odds ratios were estimated using generalized linear mixed models (GLMMs) with random intercepts for individual subjects.

Model 1: adjusted for age, follow-up time, and time from baseline to delivery date, race, education at baseline, and income at baseline

Model 2: Model 1 + time-varying parity, cumulative pregnancies and multiple gestation.