Table 2. Reported side effects associated with treatment agents used prior to adalimumab .

Agents with side effect*, N (%)	Reported side effect*, N
Azathioprine, 22 (15.1)	Anemia, 2 Lymphopenia, 4 Fatigue, 6 Renal function test impairment, 2 Liver function test impairment, 9
Steroid, 20 (13.7)	Cushing syndrome, 5 Acne, 1 Osteoporosis, 4 Neuropathy/myopathy, 2 Steroid-responder glaucoma, 9 Central serous chorioretinopathy, 1
Cyclosporine, 17 (11.6)	Fatigue; 1 Renal function test impairment, 2 Neuropathy/myopathy, 8 Hirsutism, 3 Gingival hypertrophy, 3
Interferon-α, 13 (8.9)	Lymphopenia, 3 Fatigue, 4 Liver function test impairment, 2 Alopecia, 3 Weight loss, 3 Depression, 1
Methotrexate, 10 (6.8)	Anemia, 1 Nausea, 4 Liver function test impairment, 4 Shingles (herpes zoster), 1
Etanercept, 6 (4.1)	Paradoxical uveitis, 6

N: Number of patients

*Overlapping side effects in the same patient and/or different side effects to the same agent. The most common side effect against the agent is written in bold type