Figure 1. Trends in blood culture metrics before, during, and after the bottle supply shortage.

(A) Weekly trends in the total number of blood culture submissions, (B) weekly trends in the single-set submission rate, (C) weekly trends in the blood culture submission episode numbers, (D) weekly trends in the true-positivity rate, and (E) weekly trends in the contamination rate from January to October 2024 are shown. Dots represent observed weekly values, and the solid line indicates predicted values based on segmented regression using the Prais-Winsten method. Vertical dashed lines mark the start and end of the blood culture bottle shortage period, corresponding to epidemiological week 27 (beginning July 1, 2024) and week 38 (ending September 21, 2024), respectively.