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. 2025 Jul 23;17(7):e88583. doi: 10.7759/cureus.88583

Table 3. Association of cotinine levels and environmental factors with asthma severity.

p < 0.05 is considered significant.

S. no. Variable Total, n (%) Mild severity (45), n (%) Moderate/severe severity (47), n (%) χ² p-Value
1 Cotinine levels Passive smoking 32 (34.8) 11 (24.4) 21 (44.7) 4.150 0.043
Detectable/negative 60 (65.2) 34 (75.6) 26 (55.3)
2 Residence Rural 50 (54.3) 27 (60.0) 23 (49.0) 1.134 0.291
Urban 42 (45.7) 18 (40.0) 24 (51.0)
3 Seasonal variation Yes 24 (26.0) 11 (24.4) 16 (34.0) 0.123 0.725
No 68 (74.0) 34 (75.6) 31 (66.0)
4 Cold air Yes 46 (50.0) 20 (44.4) 26 (55.3) 1.088 0.307
No 46 (50.0) 25 (55.6) 21 (44.7)
5 Dust Yes 17 (18.5) 7 (15.6) 10 (21.3) 0.450 0.479
No 75 (81.5) 38 (84.4) 37 (78.7)
6 Respiratory infections Yes 15 (16.3) 13 (28.9) 13 (27.6) 0.0171 0.895
No 77 (83.7) 32 (71.1) 34 (72.4)
7 Others Yes 14 (15.2) 5 (11.1) 9 (19.1) 0.060 0.806
No 78 (84.8) 40 (88.9) 38 (80.9)