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. Author manuscript; available in PMC: 2025 Aug 25.
Published in final edited form as: Int J Hyperthermia. 2025 Aug 11;42(1):2544017. doi: 10.1080/02656736.2025.2544017

Table 2.

Combination Index data for ART, rhTRAIL and hyperthermia.

Drug Combination Combination Index (CI) Effect
5 μM ART + Heat 0.72082 Moderate Synergy
10 μM ART + Heat 0.67044 Moderate Synergy
1 ng/mL rhTRAIL + Heat 0.69660 Moderate Synergy
2 ng/mL rhTRAIL + Heat 0.67728 Moderate Synergy
5 μM ART + 1 ng/mL rhTRAIL 0.00386 Strong Synergy
5 μM ART + 2 ng/mL rhTRAIL 0.00651 Strong Synergy
10 μM ART + 1 ng/mL rhTRAIL 0.00149 Strong Synergy
10 μM ART + 2 ng/mL rhTRAIL 0.00127 Strong Synergy
5 μM + 1 ng/mL rhTRAIL + Heat 0.57410 Moderate Synergy
5 μM + 2 ng/mL rhTRAIL + Heat 0.56592 Moderate Synergy
10 μM + 1 ng/mL rhTRAIL + Heat 0.52348 Moderate Synergy
10 μM + 2 ng/mL rhTRAIL + Heat 0.50462 Moderate Synergy