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Factors and responses with formulation parameters.
| S.No | Independent variables (factors) |
|---|---|
| X1 | Stirring speed (rpm) |
| X2 | Surfactant concentration (%) |
| X3 | Polymer concentration (gm) |
| Dependent variables (responses) | |
| Y1 | Particle size (nm) |
| Y2 | PDI (%) |
| Y3 | Entrapment efficiency (%) |
| Formulation parameters that were kept constant | |
| Z1 | Methanol 15 mL |
| Z2 | Oil concentration 200 μL |
| Z3 | Total volume 55 mL |
| Level of significance (α) 0.05 |
