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. 2025 Aug 8;13:1555449. doi: 10.3389/fchem.2025.1555449

TABLE 4.

Regression analysis summary for various data fitting models.

Model R 2 Adjusted R 2 SD Mean % CV p-value
Response Y1
 Quadratic 0.9585 0.8952 46.77 318.10 14.70 0.0018
 Linear 0.5513 0.4392 108.17 318.10 34.01 0.0187
 2FI 0.7598 0.5996 91.40 318.10 28.73 0.0189
Response Y2
 Quadratic 0.9684 0.9210 0.022 0.3460 6.45 0.0008
 Linear 0.6017 0.5021 0.056 0.3460 16.18 0.0095
 2FI 0.7171 0.5286 0.054 0.3460 15.74 0.0361
 Response Y3
 Quadratic 0.9333 0.8331 2.30 75.39 3.05 0.0067
 Linear 0.4792 0.3489 4.54 75.39 6.02 0.0435
 2FI 0.5959 0.3265 4.62 75.39 6.12 0.1369

Y1, particle size; Y2, PDI; Y3, entrapment efficiency; R 2, coefficient of correlation; CV, coefficient of variation.