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. 2025 Aug 8;16:1642150. doi: 10.3389/fneur.2025.1642150

Table 2.

Injured sciatic nerves T2 and IVIM parameters in EA, EA + BMSCs, BMSCs and PBS (mean ± SD).

MRI Time points
(weeks)
EA EA + BMSCs BMSCs PBS p < 0.05
T2 0 49.10 ± 4.61 49.63 ± 4.74 49.75 ± 3.92 48.23 ± 2.35
1 94.24 ± 4.01 93.79 ± 3.23 102.34 ± 6.32 103.05 ± 5.60 bcde
2 75.33 ± 2.84 76.90 ± 3.30 85.60 ± 6.24 85.13 ± 3.94 bcde
3 54.56 ± 3.13 53.61 ± 3.42 58.85 ± 3.65 67.04 ± 3.50 cdef
4 49.11 ± 4.49 49.41 ± 3.73 51.20 ± 4.24 60.68 ± 3.50 cef
f 0 0.0454 ± 0.0027 0.0460 ± 0.0035 0.0455 ± 0.0038 0.0455 ± 0.0044
1 0.0164 ± 0.0017 0.0167 ± 0.0020 0.0156 ± 0.0018 0.0072 ± 0.0024 cef
2 0.0296 ± 0.0065 0.0258 ± 0.0027 0.0216 ± 0.0073 0.0127 ± 0.0023 bcef
3 0.0264 ± 0.0046 0.0236 ± 0.0026 0.0213 ± 0.0031 0.0148 ± 0.0021 bcef
4 0.0374 ± 0.0047 0.0349 ± 0.0021 0.0316 ± 0.0037 0.0225 ± 0.0035 bcef
D 0 0.0014 ± 0.0002 0.0012 ± 0.0001 0.0013 ± 0.0001 0.0012 ± 0.0001
1 0.0014 ± 0.0002 0.0014 ± 0.0005 0.0013 ± 0.0001 0.0016 ± 0.0005
2 0.0016 ± 0.0005 0.0013 ± 0.0002 0.0012 ± 0.0001 0.0013 ± 0.0001
3 0.0013 ± 0.0003 0.0012 ± 0.0002 0.0013 ± 0.0003 0.0014 ± 0.0004
4 0.0013 ± 0.0001 0.0011 ± 0.0001 0.0011 ± 0.0001 0.0011 ± 0.0001
D* 0 0.0550 ± 0.0590 0.0748 ± 0.0613 0.0396 ± 0.0448 0.0284 ± 0.0154
1 0.0310 ± 0.0477 0.0148 ± 0.0027 0.0135 ± 0.0030 0.0101 ± 0.0015
2 0.0142 ± 0.0022 0.0438 ± 0.0442 0.0494 ± 0.0612 0.0299 ± 0.0480
3 0.0720 ± 0.0646 0.0340 ± 0.0464 0.0321 ± 0.0471 0.0368 ± 0.0455
4 0.0250 ± 0.0119 0.0399 ± 0.0449 0.0721 ± 0.0636 0.0451 ± 0.0439

EA, electroacupuncture; BMSCs, bone mesenchymal stem cells; PBS, phosphate-buffered saline; SD, standard deviation; p ≤ 0.05, post-hoc analysis with Bonferroni correction; f, perfusion fraction; D, diffusion coefficient; D*, pseudo-diffusion coefficient. p < 0.05 and statistically significant difference between groups: b, EA vs. BMSCs; c, EA vs. PBS; d, EA + BMSCs vs. BMSCs; e, EA + BMSCs vs. PBS; f, BMSCs vs. PBS.