Table 1. A comparative analysis of diagnostic tests between patients with PCOS and patients at risk for PCOS .
|
- |
PCOS (n=35) |
At risk (n=200) |
p |
|
LH (IU/L) |
9.58±4.20 |
9.34±6.6 |
0.839 |
|
FSH (IU/L) |
4.31±1.15 |
4.94±1.44 |
0.033* |
|
Estradiol (pg/mL) |
45.9 (27) |
39.1 (22.6) |
0.358 |
|
Total testosterone (ng/mL) |
0.56±0.20 |
0.46±0.25 |
0.043* |
|
SHBG (nmol/L) |
15.5 (8.18) |
20.0 (12.5) |
0.002* |
|
Free androgen index |
11.6 (6.8) |
8.0 (7.0) |
<0.001* |
|
17-hydroxyprogesterone (ng/mL) |
1.36 (1.04) |
1.07 (0.97) |
0.020* |
|
1,4-androstenedione (ng/mL) |
4.36 (1.28) |
3.33 (1.61) |
0.003* |
|
DHEAS (mcg/dL) |
289 (202) |
313 (164) |
0.598 |
|
LH/FSH ratio |
2.24±0.89 |
1.92±1.29 |
0.182 |
*p<0.05. Normally distributed data were compared by independent-samples t-test and results were expressed as mean±standard deviation; non-normally distributed data were compared by Mann-Whitney U test and results were expressed as median and IQR.
SHBG: sex hormone binding globulin, DHEAS: dehydroepiandrostenedione sulfate, PCOS: polycystic ovary syndrome, IQR: interquartile range, LH/FSH: luteinising hormone/follicle stimulating hormone