Table 1. Baseline data of 52 newborns (patients group vs. control group) .
|
Variables |
Patients (n=32) |
Control group (n=20) |
p value |
|
Gender M/F |
18/14 |
13/7 |
0.371 |
|
Age (day) |
19±7 (7-30) |
22±8 (14-30) |
0.136 |
|
Length SDS |
-0.34±0.72 |
-0.51±0.75 |
0.26 |
|
Weight SDS |
-0.041±0.77 |
-0.35±1.1 |
0.24 |
|
Body mass index (kg/m2) |
14.18±1.56 |
14.42±1.90 |
0.418 |
|
Head circumference SDS |
0.043±0.80 |
-0.27±0.77 |
0.16 |
|
Mother’s thyroid disorder history |
7/32 (21%) |
1/20 (0.5%) |
<0.001 |
|
fT3 (pmol/L) |
3.14±2.01 |
6.06±0.86 |
<0.001 |
|
fT4 (pmol/L) |
6.31±2.64 |
14.99±2.03 |
<0.001 |
|
TSH (mU/L) |
280.99±297.37 |
2.47±0.74 |
<0.001 |
|
Thyroglobulin (ng/mL) |
1482.68±1351.97 |
67.74±39.90 |
0.002 |
|
Urinary iodine (mcg/L) |
400.83±334.23 |
173.11±96.73 |
<0.001 |
|
Neudesin level* (ng/mL) |
6.77±6.41 |
7.93±7.04 |
0.552 |
|
Thyroid USG |
Agenesis: 3 Hemi-agenesis: 1 Goiter: 2 Normal: 26 |
- |
- |
*Baseline neudesin levels.
M: male, F: female, fT3: free triiodothyronine, fT4: free thyroxine, TSH: thyroid stimulating hormone, Tg: thyroglobulin, USG: ultrasonography, SDS: standard deviation score