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. 2025 Aug 22;17(3):263–268. doi: 10.4274/jcrpe.galenos.2025.2024-1-14

Table 2. Effect of levothyroxine sodium treatment on anthropometric measures, thyroid hormone, and neudesin levels .

-

Patients before treatment

Patients after treatment

p

Length SDS

-0.03±0.72

-0.15±0.66

0.41

Weight SDS

-0.42±0.77

-0.01±0.51

0.76

BMI

14.23±1.49

15.76±1.32

<0.001

BMI SDS

-0.13±0.91

0.41±0.62

<0.001

Head circumference SDS

-0.43±0.80

-0.18±0.75

0.15

fT4 (pmol/L)

6.31±2.64

20.92±3.97

<0.001

TSH (mU/L)

280.99±297.37

170.23 (32.93, 1100)

4.89±16.07

1.52 (0.08, 24.12)

<0.001

Neudesin level* (ng/mL)

6.46±6.63

3.93 (0.31, 30.06)

12.85±18.74

6.15 (2.17, 70.05)

0.019

*The second blood sample obtained only in 26 of 32 children.

Non-normally distributed parameters were also presented as median (minimum, maximum).

fT4: free thyroxine, TSH: thyroid stimulating hormone, BMI: body mass index, SDS: standard deviation score