Table 2. Effect of levothyroxine sodium treatment on anthropometric measures, thyroid hormone, and neudesin levels .
|
- |
Patients before treatment |
Patients after treatment |
p |
|
Length SDS |
-0.03±0.72 |
-0.15±0.66 |
0.41 |
|
Weight SDS |
-0.42±0.77 |
-0.01±0.51 |
0.76 |
|
BMI |
14.23±1.49 |
15.76±1.32 |
<0.001 |
|
BMI SDS |
-0.13±0.91 |
0.41±0.62 |
<0.001 |
|
Head circumference SDS |
-0.43±0.80 |
-0.18±0.75 |
0.15 |
|
fT4 (pmol/L) |
6.31±2.64 |
20.92±3.97 |
<0.001 |
|
TSH (mU/L) |
280.99±297.37 170.23 (32.93, 1100) |
4.89±16.07 1.52 (0.08, 24.12) |
<0.001 |
|
Neudesin level* (ng/mL) |
6.46±6.63 3.93 (0.31, 30.06) |
12.85±18.74 6.15 (2.17, 70.05) |
0.019 |
*The second blood sample obtained only in 26 of 32 children.
Non-normally distributed parameters were also presented as median (minimum, maximum).
fT4: free thyroxine, TSH: thyroid stimulating hormone, BMI: body mass index, SDS: standard deviation score