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. 2025 Jul 1;51(6-7):223–237. doi: 10.14745/ccdr.v51i67a02

Table 4. Estimated chronic hepatitis C prevalence for the general population and key populations, Canada, 2021.

Population Population size estimate Prevalence (%) Estimated number of people living with CHC Reference(s)
Point estimate Lower bound Upper bound Point estimate Lower bound Upper bound
General population 38,239,864 0.56% 0.15% 0.97% 214,000 58,500 369,000 ((12,21,30,31,4852))
PWID, within 12 months 100,300 36.9% 12.6% 55.1% 37,000 12,600 55,300 ((3235,53,54))
Unpublished data from the HEPCO study, 2022–2023 (personal communication, Sarah Larney, 2024)
Unpublished data from the Virtual Cascade of Care Cohort study, 2018–2019 (personal communication, Stine Høj, 2023)
People who have ever injected drugs 388,400 18.1% 5.7% 30.5% 70,100 21,900 118,000 ((21,35))
Unpublished data from the Virtual Cascade of Care Cohort study, 2018–2019 (personal communication, Stine Høj, 2023)
People incarcerated in provincial prisonsa 18,950 5.1% 4.4% 5.7% 957 834 1,080 ((38,40,41))
Unpublished data from Alberta Health Services, 2023 (personal communication, Kaylee Goralcyk, 2024)
First Nations 1,048,400 3.3% 1.5% 5.0% 34,300 15,800 52,800 ((4244,55,56))
People incarcerated in federal prisonsb 12,405 3.2% 2.7% 3.7% 396 335 464 Unpublished data from Correctional Service Canada, 2021 (personal communication, 2024)
Immigrants from countries where hepatitis C is common (≥2% seroprevalence) 1,276,405 2.2% 1.6% 3.5% 28,100 19,800 44,600 ((25))
Adults in the 1945–1975 birth cohort 14,267,340 1.1% 0.21% 2.0% 157,000 30,000 284,000 ((12,21,48,49,57))
GBMSM 669,613 0.94% 0.18% 1.7% 6,290 1,210 11,400 ((27,45,46))
Unpublished data from the Engage cohort study 2017–2019
Inuit Insufficient information
Métis Insufficient information

Abbreviations: CHC, chronic hepatitis C; HEPCO, Hepatitis Cohort; GBMSM, gay, bisexual and other men who have sex with men; PWID, people who inject drugs

a Who were sentenced for two years or more

b Who were sentenced for less than two years