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. 2025 Jan 28;111(3):2331–2337. doi: 10.1097/JS9.0000000000002256

Table 3.

Comparison of RLPN-OS and several preoperative lung nodule localization methods in terms of success rates, complications, and costs

Localization technique Study Sample size Success rates Complications Required equipment and costs
Pneumothorax Hemorrhage
Hook-wire Li et al. 2015[18] 46 93% 37% 21% Hook-wire and CT scanning, Inexpensive, about 1000 RMB
Ichinose et al. 2013[19] 417 100% 68% 10.00%
Iguchi et al. 2015[20] 11 91% 55% 36%
Suzuki et al. 2014[21] 161 98% 38% 35.00%
Seo et al. 2012[22] 174 95% 40% 36%
Huang et al. 2014[23] 41 95% 13% 5.20%
Microcoil Liu et al. 2014[24] 23 100% 9% 18% Microcoil and CT scanning, Inexpensive, about 1000 RMB
Finley et al. 2015[6] 29 93% 14% 0
Su et al. 2015[25] 101 98% 16% 17%
Sui et al. 2015[26] 98 100% 13% 4%
Methylene blue Zhou et al. 2020[27] 129 95% 10% 3% Methylene blue and CT scanning, Inexpensive, about 800 RMB
Sun et al. 2020[28] 47 98% 4% -
Zhang et al. 2022[29] 32 100% 10% 10%
Lipiodol Kawanaka et al. 2009[30] 107 100% 31% 15% Lipiodol, CT scanning and detection devices, about 1500 RMB
Kim et al. 2011[31] 68 99% 29% 7%
Miura et al. 2015[32] 103 100% 61% 35%
Mogi et al. 2015[33] 56 98% 38% 16%
ENB Kuo et al. 2019[34] 15 100% 7% 20% Electromagnetic navigation bronchoscopy system, Expensive, about 10 000 RMB
Zhang et al. 2021[35] 181 98% 0% 0%
Yang et al. 2021[36] 12 100% 0% 0%
RAB Liu et al. 2023[11] 33 100% 0% 0% Robot-assisted bronchoscopy system, expensive, about 30 000 RMB
RLPN-OS - 78 99% 0% 2.60% Inexpensive needles and free locator ruler for almost 0 cost

ENB, electromagnetic navigation bronchoscopy; RAB, robot-assisted bronchoscopy.