Skip to main content
. 2025 Aug 18;19:7089–7098. doi: 10.2147/DDDT.S528786

Table 1.

Cosentino Classification of Testicular Damage19

Grade 1 Normal testicular structure with an orderly arrangement of germinal cells
Grade 2 Less orderly, non-cohesive germinal cells and closely packed seminiferous tubules
Grade 3 Disordered sloughed germinal cells with shrunken pyknotic nuclei and impaired borders of the seminiferous tubules
Grade 4 Seminiferous tubules tightly surrounded by coagulative necrosis of germinal cells