. 2025 Aug 22;11(34):eadx2434. doi: 10.1126/sciadv.adx2434

Table 2. Atomic distance measurements to define kinase conformation.

Distance measurements performed as previously described (43) in PyMOL (80).

Structures	D1: Leu⁶⁸.CA-Phe¹⁵⁸.A CZ	D2: Lys⁴⁵.CA-Phe¹⁵⁸.CZ	Lys⁴⁵.CB-Glu⁶⁴.CB
α2KD–BAY-3827	12.4 Å	18.4 Å	11.7 Å
AMPKα2 (T172D)–KD-compound C (PDB: 3AQV)	11.4 Å	16.6 Å	11.3 Å
AMPKα2 (T172D)–KD-SBI-0206965 (PDB: 6BX6)	13.1 Å	18.2 Å	11.8 Å