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. 2025 Aug 22;11(34):eadu7319. doi: 10.1126/sciadv.adu7319

Fig. 3. Validation of BayROM based on biological samples.

Fig. 3.

(A) Comparison of hyperspectral images of WAT using full raster scanning (GT) and BayROM (RC). The average RMSE and the average PSNR between GT and BayROM are 12.44 μV and 35.1 dB. au, arbitrary unit; h, hours. (B) Comparison of zoomed-in areas between GT and BayROM. (C) Comparison of reconstruction and GT using cross-sectional intensity plots in the x and y directions for each excitation wave number. (D) Quantitative comparison of reconstruction and GT with indicated MAE. (E) Comparison of data reduction levels. A data reduction level of 92.5% enables high reconstruction quality and ~10 times faster data acquisition. (F) Comparison of pixel-wise errors for data reduction levels shown in (E). (G and H) Image comparisons of large FOVs, i.e., 5 mm by 5 mm, and small FOVs, i.e., 1 mm by 1 mm, of mouse muscle, and pancreatic tissues imaged using full raster scanning (GT) and BayROM (92.5% data reduction). For the muscle tissue scans, the average RMSE and PSNR between GT and BayROM are 11.91 μV and 32.96 dB for the large FOVs, and 6.836 μV and 34.04 dB for the small FOVs. For the pancreatic tissue scans, the average RMSE and the average PSNR between GT and BayROM are 34.42 μV and 28.12 dB for the large FOVs, and 15.79 μV and 33.02 dB for the small FOVs. (I and J) Image comparisons of large FOVs, i.e., 5 mm by 5 mm, of mouse liver and kidney tissues imaged using full raster scanning (GT) and BayROM. For the liver tissue scans, the average RMSE and the average PSNR between GT and BayROM are 8.304 μV and 31.24 dB. For the kidney tissue scans, the average RMSE and the average PSNR between GT and BayROM are 5.853 μV and 36.89 dB.