. 2025 Aug 21;66(11):49. doi: 10.1167/iovs.66.11.49

Table 4.

Longitudinal Evaluation of OCTA Metrics Using Estimated Marginal Means With Post Hoc Dunnett's Tests

	Ocular Severity	Baseline	6 Mo	P Value^†	1 Y	P Value^§
GPD-SCP, %	Non-referable	8.43 ± 0.71	9.12 ± 0.76	0.273	9.39 ± 0.76	0.101
	Referable	13.04 ± 0.54	13.31 ± 0.58	0.678	14.41 ± 0.58	<0.001 ^*
	Entire	10.74 ± 0.46	11.22 ± 0.49	0.208	11.90 ± 0.49	<0.001 ^*
GPD-DCP, %	Non-referable	3.43 ± 0.39	3.50 ± 0.42	0.949	3.70 ± 0.42	0.577
	Referable	5.82 ± 0.30	6.36 ± 0.33	0.036 ^*	6.41 ± 0.32	0.016 ^*
	Entire	4.63 ± 0.26	4.93 ± 0.28	0.193	5.06 ± 0.28	0.045 ^*
VD-SCP, %	Non-referable	45.00 ± 0.50	44.75 ± 0.70	0.804	43.50 ± 0.70	0.004 ^*
	Referable	41.06 ± 0.54	40.65 ± 0.54	0.408	40.33 ± 0.54	0.061
	Entire	43.03 ± 0.43	42.70 ± 0.46	0.429	41.92 ± 0.46	<0.001 ^*
VD-DCP, %	Non-referable	47.90 ± 0.49	48.23 ± 0.55	0.728	48.14 ± 0.56	0.849
	Referable	45.33 ± 0.36	45.47 ± 0.42	0.896	45.24 ± 0.41	0.944
	Entire	46.62 ± 0.30	46.85 ± 0.34	0.674	46.69 ± 0.35	0.954
VLD-SCP, mm⁻¹	Non-referable	15.82 ± 0.27	15.94 ± 0.30	0.780	15.31 ± 0.30	0.057
	Referable	14.03 ± 0.20	13.81 ± 0.23	0.334	13.55 ± 0.22	0.008 ^*
	Entire	14.92 ± 0.17	14.88 ± 0.19	0.912	14.43± 0.19	0.001 ^*
VLD-DCP, mm⁻¹	Non-referable	19.39 ± 0.21	19.63 ± 0.23	0.287	19.40 ± 0.23	0.992
	Referable	17.73 ± 0.16	17.64 ± 0.17	0.693	17.36 ± 0.17	0.006 ^*
	Entire	18.56 ± 0.13	18.63 ± 0.15	0.714	18.38 ± 0.15	0.169
FAZ area, mm²	Non-referable	0.312 ± 0.023	0.311 ± 0.023	0.994	0.311 ± 0.023	0.996
	Referable	0.399 ± 0.017	0.413 ± 0.017	0.102	0.413 ± 0.017	0.066
	Entire	0.355 ± 0.014	0.362 ± 0.015	0.435	0.362 ± 0.015	0.389

^†

Comparison between 6 mo and baseline follow-ups.

^§

Comparison between 1-y and baseline follow-ups using Dunnett's multiple comparison test.

P < 0.05.

Data were presented as estimated marginal means ± standard errors. All analyses were performed at the eye level, with intra-patient correlation accounted for by including patient as a random effect in the linear mixed models used to generate the estimated marginal means.

The P values in bold represent statistical significance.