Figure 5.

A) Timeline of the male c57Bl/6J fecal material transplant recipient mice cohorts. Weeks of intervention listed at bottom. Orange, red, and green represent PB2 (n=9), PB2+Sham stool (n=10) and PB2+Sleeve stool (n=10) treatments respectively. The stool icon represents weeks that stool for 16s sequencing was taken. Week 18 represents the end of the experiment in which 16s, serum bile acid, and hepatocyte transcription analyses were performed. B) Weight gain experienced by all male c57Bl/6J fecal material transfer groups shown as grams gained per week of 45% HFD and stool treatment. ns= non-significant differences for each week between groups with a p-value <0.05. C) Absolute weight gain experienced by all male C57Bl/6J fecal material transfer groups shown as grams gained per week of 45% HFD and stool treatment. ns= non-significant differences for each week between groups with a p-value <0.05 D) Cumulative grams of 45% HFD food eaten by all male c57Bl/6J fecal material transfer groups throughout the experiment. Error bars represent standard error of the mean.