Table 3.

Separate Structural Equation Models Testing Mediation in the Intergenerational Transmission of Depression

Mediator	Path/Effect	β	SE(β)	p	RMSEA	CFI	R2 Youth Depression
Negative Emotionality	IV to MED	.21	.06	.004	0.074	0.930	.22
	MED to DV	.47	.10	≦ t.001
	IV to DV	.01	.06	.815
	Indirect Effect	.10	.04	.021
Positive Emotionality	IV to MED	-.07	.07	.391	0.059	0.949	.07
	MED to DV	-.26	.09	.008
	IV to DV	.09	.05	.124
	Indirect Effect	.02	.02	.459
Disinhibition	IV to MED	.08	.06	.182	0.069	0.950	.05
	MED to DV	.20	.07	.013
	IV to DV	.09	.06	.103
	Indirect Effect	.02	.01	.263
Cognitive Biases	IV to MED	.25	.66	.007	0.044	0.968	.23
	MED to DV	.48	.09	≦ .001
	IV to DV	-.02	.05	.709
	Indirect Effect	.12	.04	.005
Neural Processing of Emotional Stimuli	IV to MED	-.05	.09	.519	0.040	0.973	.03
	MED to DV	-.12	.01	.521
	IV to DV	.10	.05	.094
	Indirect Effect	.01	.02	.682
Subthreshold Depressive Symptoms	IV to MED	.17	.07	.009	0.082	0.930	.38
	MED to DV	.62	.08	≤ .001
	IV to DV	<.01	.05	.943
	Indirect Effect	.11	.04	.018
Anxiety Symptoms	IV to MED	.22	.05	≤ .001	0.055	0.963	.12
	MED to DV	.33	.08	≤ .001
	IV to DV	.05	.06	.425
	Indirect Effect	.07	.02	.006
Irritability	IV to MED	.19	.06	.022	0.068	0.943	.16
	MED to DV	.39	.10	.002
	IV to DV	.03	.06	.588
	Indirect Effect	.08	.03	.025
Interpersonal Functioning	IV to MED	.04	.06	.480	0.060	0.931	.14
	MED to DV	.36	.10	.002
	IV to DV	.10	.05	.064
	Indirect Effect	.02	.02	.517

Note: IV to MED = Path for number of depressed parents to hypothesized mediator; MED to DV= Path for mediator to youth depression; IV to DV = Path for parental depression to youth depression; Indirect Effect=Effect for number of depressed parents to youth depression via hypothesized mediator; β=standardized beta; p=unstandardized p-value; R² Youth Depression=Total variance explained in predicting youth depression across pathways tested; RMSEA = Root Mean Square Error of Approximation; CFI = Comparative Fit Index.