Table 4.

Structural Equation Model Examining the Unique Effects of Mediators of the Intergenerational Transmission of Depression

Mediator	Path/Effect	β	SE(β)	p	RMSEA	CFI	R2 Youth Depression
Negative Emotionality	IV to MED	.19	.06	.004	0.062	0.953	.36
	IV to SX	.16	.06	.013
	MED to DV	.01	.16	.930
	SX to DV	.59	.16	≤.001
	IV to DV	.01	.05	.889
	Indirect Effect MED	.03	.02	.932
	Indirect Effect SX	.09	.05	.049
	MED with SX	.72	.06	≤.001
Positive Emotionality	IV to MED	-.06	.343	.380	0.063	0.943	.38
	IV to SX	.17	.06	.009
	MED to DV	.13	.10	.247
	SX to DV	.67	.11	≤.001
	IV to DV	≤.01	.05	.993
	Indirect Effect MED	-.01	.01	.525
	Indirect Effect SX	.12	.05	.021
	MED with SX	-.58	.06	≤.001
Disinhibition	IV to MED	.08	.06	.174	0.068	0.944	.39
	IV to SX	.17	.06	.008
	MED to DV	-.16	.08	.046
	SX to DV	.70	.10	≤.001
	IV to DV	≤.01	.05	.962
	Indirect Effect MED	-.01	.01	.276
	Indirect Effect SX	.12	.05	.012
	MED with SX	.58	.06	≤.001
Cognitive Biases	IV to MED	.24	.06	≤.001	0.059	0.938	.36
	IV to SX	.12	.06	.003
	MED to DV	-.06	.10	.576
	SX to DV	.65	.04	≤.001
	IV to DV	.03	.05	.402
	Indirect Effect MED	-.01	.03	.591
	Indirect Effect SX	.08	.04	.038
	MED with SX	.99	.02	≤.001
Neural Processing of Emotional Stimuli	IV to MED	.05	.09	.523	0.056	0.939	.39
	IV to SX	.16	.06	.010
	MED to DV	-.05	.09	.825
	SX to DV	.61	.08	≤.001
	IV to DV	≤.01	.05	.972
	Indirect Effect MED	≤.01	.01	.831
	Indirect Effect SX	.10	.04	≤.001
	MED with SX	-.11	.11	.269
Anxiety Symptoms	IV to MED	.21	.05	≤.001	0.067	0.942	.39
	IV to SX	.20	.06	.003
	MED to DV	.06	.08	.487
	SX to DV	.59	.11	≤.001
	IV to DV	.01	.05	.801
	Indirect Effect MED	.01	.02	.492
	Indirect Effect SX	.11	.05	.016
	MED with SX	.47	.09	.015
Irritability	IV to MED	.19	.06	.015	0.066	0.944	.36
	IV to SX	.17	.06	.009
	MED to DV	.06	.13	.649
	SX to DV	.56	.13	≤.001
	IV to DV	≤.01	.02	.975
	Indirect Effect MED	.01	.05	.656
	Indirect Effect SX	.10	,04	.039
	MED with SX	.69	.07	.010
Interpersonal Functioning	IV to MED	.06	.06	.345	0.067	0.907	.42
	IV to SX	.17	.06	.005
	MED to DV	-.15	.24	.565
	SX to DV	.74	.24	.004
	IV to DV	.01	.05	.912
	Indirect Effect MED	-.01	.02	.710
	Indirect Effect SX	.13	.06	.054
	MED with SX	.72	.06	≤.001

Note: IV to MED = Path for number of depressed parents to the mediator; IV to DEP SX = Path for number of parents depressed to youth subthreshold depressive symptoms; MED to DV= Path for mediator to youth depression; DEP SX to MED = Path for youth subthreshold depressive symptoms to youth depression; IV to DV = Path for number of depressed parents to youth depression; Indirect Effect MED= Effect for number of depressed parents to youth depression via hypothesized mediator; Indirect Effect DEP SX=Effect of number of depressed parents to youth depression via youth subthreshold depressive symptoms; MED with SX=Correlation between hypothesized mediator and youth subthreshold depressive symptoms; β=standardized beta; p=unstandardized p-value; R² Youth Depression=Total variance in predicting youth depression across pathways tested; RMSEA = Root Mean Square Error of Approximation; CFI = Comparative Fit Index.