Table 2. Demographic and disease-related variables of the patients with data related to the Invisible Symptoms protocol.
| Variable | Protocol sample (n=430) |
|---|---|
| Age at MSa onset (years) | |
| Mean (SD) | 33.1 (10.18) |
| Missing data, n (%) | 108 (25.1) |
| Age at MS diagnosis (years), mean (SD) | 35.5 (10.13) |
| Age at first PROb recording (years), mean (SD) | 42.5 (10.28) |
| Sex (female), n (%) | 357 (83.0) |
| Disease course, n (%) | |
| RRMSc | 354 (82.3) |
| SPMSd | 20 (4.7) |
| PPMSe | 22 (5.1) |
| UNSf | 34 (7.9) |
| Disease duration (years), median (Q1-Q3) | 4.1 (0.6-11.3) |
| EDSSg | |
| Median (IQR) | 2.5 (2.0-3.5) |
| Missing data, n (%) | 50 (12) |
| Education (total years) | |
| Mean (SD) | 14.3 (2.73) |
| Missing data, n (%) | 118 (27.4) |
| Smoking (yes), n (%) | |
| Number | 39 (10) |
| Missing data | 24 (6) |
a
MS: multiple sclerosis.
b
PRO: patient-reported outcome.
c
RRMS: relapsing-remitting MS.
d
SPMS: secondary progressive MS.
e
PPMS: primary progressive MS.
f
UNS: unspecified disease course.
g
EDSS: Expanded Disability Status Scale.