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. 2025 Aug 22;13:RP97860. doi: 10.7554/eLife.97860

Figure 7. Nifedipine ceased organoidal contractions and Ca2+ activities in ICCs.

Figure 7.

Similar experiment to Figure 6. (A) Organoidal contractions were extinguished at 1  µM. (B) Contraction intervals before and after administration, and upon washout. Median values: Before, 25.7; Nifedipine 1  µM, N/A; Washout, 22.2. Statistical significance was assessed using Welch’s t-test. **p<0.01. Sample size: n = 5. Peak counts: Before, 101; Nifedipine 1  µM, N/A; Washout, 46. (C) Ca²+ transients in a single ICC before and after administration of 1  µM nifedipine, and following washout. Scale bar: 30  µm.

Figure 7—source data 1. Time lapse data for Figure 7.
elife-97860-fig7-data1.xlsx (109.3KB, xlsx)