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. 2025 Jul 23;17(7):e88612. doi: 10.7759/cureus.88612

Table 13. Disease-free survival at 10 years - analysis of subgroups.

--: Not available/applicable

Subgroup k Effect Size (HR) (95%CI) I2 (%) p-value (subgroup difference)
RoB (Risk of Bias)
Low 5 1.1161 (0.7908; 1.5751) 96.4 --
Country
Korea 2 1.2835 (0.9720; 1.6948) 0.0 < 0.0001
China 1 0.8125 (0.5466; 1.2077) -- --
Norway 1 0.7500 (0.6777; 0.8301) -- --
USA 1 1.7143 (1.5233; 1.9292) -- --
Year
2008 1 1.2667 (0.9320; 1.7215) -- 0.3247
2022 1 0.8125 (0.5466; 1.2077) -- --
2015 2 1.1332 (0.5041; 2.5477) 99.1 --
2021 1 1.3636 (0.7066; 2.6317) -- --
Study Design
Cohort Study 5 1.1161 (0.7908; 1.5751) 96.4 --
Intervention
Breast-conserving surgery with RT 3 1.1725 (0.7181; 1.9144) 98.2 0.6163
Breast-conserving surgery 2 0.9822 (0.6024; 1.6017) 42.8 --
Type of Breast Cancer
Not specified 1 1.2667 (0.9320; 1.7215) -- 0.5578
Multiple 4 1.0812 (0.7022; 1.6648) 97.3 --
Stage of Breast Cancer
I, IIA 1 1.2667 (0.9320; 1.7215) -- < 0.0001
I, II, III, IV 1 0.8125 (0.5466; 1.2077) -- --
I, II, III 1 0.7500 (0.6777; 0.8301) -- --
I, II 1 1.3636 (0.7066; 2.6317) -- --
I, IIA, IIb 1 1.7143 (1.5233; 1.9292) -- --