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. 2025 Aug 15;2025:4661541. doi: 10.1155/da/4661541

Table 2.

Self-medication prevalence by sex in depressed and noninstitutionalized residents aged 15 and over in the European Union according to demographic, socioeconomic, and lifestyle variables.

Independent variables Recognized depression Depression symptoms Both groups
Male Female OR female Male Female OR female Male Female OR female
Total 40.52 (39.42–41.62) 45.68 (44.80–46.56) 1.23 (1.08–1.41) 33.25 (31.59–34.95) 49.87 (48.45–51.30) 1.99 (1.66–2.39) 38.46 (37.54–39.39) 46.84 (46.09–47.58) 1.41 (1.27–1.57)
Agea,b,c,d,e,f
 15–24 years 47.73 (43.92–51.41) 49.12 (46.11–52.23) 1.06 (0.64–1.73) 25.19 (20.66–30.48) 51.67 (47.20–56.12) 3.17 (2.53–4.08) 40.84 (37.79–43.93) 49.93 (47.37–52.43) 1.44 (0.97–2.14)
 25–44 years 44.35 (42.38–46.35) 54.48 (52.74–56.20) 1.50 (1.14–1.97) 43.53 (39.95–47.09) 60.76 (57.74–63.74) 2.00 (1.28–3.15) 44.16 (42.42–45.90) 56.00 (54.49–57.50) 1.60 (1.27–2.03)
 45–64 years 38.12 (36.43–39.86) 44.67 (43.24–46.11) 1.31 (1.07–1.60) 28.80 (26.05–31.68) 53.57 (50.90–56.27) 2.85 (2.07–3.92) 35.84 (34.39–37.34) 46.65 (45.39–47.93) 1.56 (1.31–1.86)
 65–74 years 35.81 (32.48–39.26) 41.38 (39.06–43.72) 1.26 (0.92–1.74) 37.99 (33.29–42.67) 45.42 (41.18–49.58) 1.36 (0.91–2.02) 36.57 (33.85–39.36) 42.34 (40.30–44.37) 1.27 (0.99–1.63)
 75+ years 36.20 (32.79–39.79) 35.50 (33.38–37.68) 0.97 (0.69–1.35) 28.67 (25.21–32.54) 39.46 (36.88–42.03) 1.62 (1.22–2.15) 32.84 (30.32–35.40) 37.17 (35.53–38.84) 1.21 (0.96–1.52)
Nationalitya,b,c,f
 Native-born 39.40 (38.21–40.58) 45.20 (44.26–46.14) 1.27 (1.10–1.45) 34.16 (32.34–36.00) 49.83 (48.32–51.33) 1.91 (1.58–2.32) 37.92 (36.93–38.92) 46.50 (45.70–47.29) 1.42 (1.27–1.59)
 Born in another EU state 41.32 (34.88–47.65) 55.62 (51.32–59.77) 1.78 (0.85–3.71) 30.14 (22.18–38.63) 49.53 (42.29–56.64) 2.27 (1.68–3.22) 37.51 (32.60–42.82) 54.05 (50.33–57.63) 1.96 (1.05–3.64)
 Born in non-EU country 48.17 (44.75–51.59) 44.71 (41.65–47.78) 0.87 (0.54–1.39) 24.28 (19.92–29.30) 50.44 (44.90–56.08) 3.17 (2.54–4.07) 41.44 (38.62–44.34) 46.04 (43.33–48.71) 1.20 (0.82–1.77)
Degree of urbanizationa,c,d,e,f
 Cities 41.98 (40.32–43.65) 46.19 (44.87–47.52) 1.19 (0.97–1.44) 36.68 (34.01–39.36) 52.29 (50.09–54.47) 1.89 (1.40–2.54) 40.55 (39.13–41.97) 47.83 (46.69–48.96) 1.34 (1.14–1.58)
 Towns and suburbs 39.40 (37.54–41.34) 44.09 (42.57–45.61) 1.21 (0.96–1.53) 30.84 (28.00–33.87) 48.76 (46.28–51.33) 2.13 (1.49–3.05) 37.08 (35.47–38.68) 45.35 (44.05–46.66) 1.40 (1.15–1.71)
 Rural areas 38.46 (36.09–40.89) 46.53 (44.65–48.40) 1.39 (1.24–1.57) 30.82 (27.68–34.09) 47.33 (44.46–50.20) 2.01 (1.55–2.62) 35.90 (33.99–37.85) 46.77 (45.21–48.35) 1.57 (1.29–1.91)
Marital statusa,b,c,d,e,f
 Single 43.23 (41.53–44.95) 49.98 (48.13–51.80) 1.31 (1.00–1.71) 35.06 (32.04–38.23) 57.07 (53.91–60.13) 2.46 (1.58–3.83) 41.43 (39.95–42.95) 51.78 (50.20–53.37) 1.52 (1.21–1.90)
 Married or living with partner 38.70 (37.00–40.44) 46.04 (44.76–47.34) 1.35 (1.15–1.59) 35.76 (33.31–38.32) 50.34 (48.06–52.58) 1.82 (1.46–2.27) 37.78 (36.36–39.20) 47.10 (45.98–48.22) 1.47 (1.28–1.67)
 Divorced 34.68 (30.19–39.18) 38.30 (36.24–40.37) 1.17 (0.60–2.04) 27.24 (22.75–32.18) 43.47 (40.86–46.16) 2.05 (1.30–3.25) 31.38 (28.10–34.64) 40.30 (38.68–41.94) 1.48 (1.01–2.16)
 Widowed 39.85 (36.66–42.97) 46.56 (44.19–48.93) 1.31 (0.90–1.91) 24.56 (20.28–29.04) 53.09 (48.79–57.40) 3.47 (1.95–6.18) 35.48 (32.90–38.12) 48.08 (46.02–50.18) 1.68 (1.22–2.32)
Education levela,b,c,d,e,f
 No formal education 25.44 (18.44–32.98) 13.10 (10.33–16.36) 0.44 (0.18–0.82) 26.87 (16.95–38.25) 24.29 (17.65–31.96) 0.87 (0.51–1.49) 25.90 (20.05–32.17) 15.57 (12.88–18.61) 0.53 (0.31–0.86)
 Primary school 32.50 (30.54–34.48) 36.10 (34.69–37.53) 1.17 (0.88–1.56) 24.13 (21.54–26.85) 41.33 (39.14–43.57) 2.21 (1.57–3.12) 29.87 (28.30–31.48) 37.68 (36.49–38.89) 1.42 (1.13–1.78)
 Secondary school 43.61 (42.04–45.16) 51.65 (50.31–52.99) 1.38 (1.13–1.68) 35.20 (32.75–37.68) 55.86 (53.59–58.11) 2.32 (1.73–3.13) 41.34 (40.03–42.68) 52.74 (51.58–53.89) 1.58 (1.34–1.87)
 Higher education 45.37 (42.75–48.03) 58.00 (55.92–60.10) 1.66 (1.37–2.01) 46.48 (42.06–50.78) 61.96 (58.55–65.36) 1.87 (1.40–2.51) 45.67 (43.40–47.92) 59.06 (57.29–60.86) 1.72 (1.46–2.01)
Employment statusa,b,c,d,e,f
 Employed 38.96 (36.91–41.02) 44.27 (42.67–45.91) 1.48 (1.19–1.82) 24.47 (21.70–27.43) 48.76 (46.04–51.49) 1.83 (1.29–2.59) 34.82 (33.14–36.54) 45.45 (44.07–46.86) 1.56 (1.30–1.87)
 Unemployed 43.58 (41.19–45.96) 41.88 (40.11–43.70) 1.09 (0.67–1.78) 29.95 (26.56–33.49) 45.14 (42.25–48.13) 4.80 (2.23–10.37) 39.66 (37.67–41.65) 42.78 (41.25–44.31) 1.42 (0.92–2.20)
 Inactive 40.13 (37.62–42.70) 44.84 (42.78–46.90) 1.13 (095–1.35) 36.49 (32.60–40.45) 51.84 (48.47–55.23) 2.11 (1.72–2.60) 39.09 (36.96–41.23) 46.74 (45.00–48.53) 1.37 (1.19–1.57)
Income levela,b,c,d,e,f
 1st quintile 38.17 (35.44–41.01) 49.04 (46.76–51.33) 1.24 (0.94–1.65) 41.87 (37.50–46.65) 52.61 (48.76–56.35) 2.94 (1.95–4.42) 39.19 (36.81–41.57) 49.99 (48.04–51.96) 1.56 (1.23–1.97)
 2nd quintile 43.04 (39.93–46.32) 49.63 (46.98–52.35) 0.93 (0.69–1.26) 42.52 (37.24–47.91) 56.41 (52.28–60.46) 1.92 (1.37–2.71) 42.90 (40.22–45.71) 51.65 (49.39–53.88) 1.14 (0.89–1.45)
 3rd quintile 43.23 (41.48–44.98) 53.03 (51.51–54.51) 1.21 (0.91–1.61) 44.43 (41.43–47.42) 59.37 (56.77–61.91) 1.87 (1.51–3.04) 43.54 (42.05–45.07) 54.60 (53.30–55.89) 1.37 (1.07–1.75)
 4th quintile 35.81 (32.58–39.26) 37.94 (35.06–40.88) 1.56 (1.18–2.05) 20.16 (15.43–25.85) 54.83 (47.65–61.78) 1.54 (1.06–2.24) 32.32 (29.46–35.21) 40.48 (37.77–43.20) 1.55 (1.24–1.94)
 5th quintile 39.23 (37.67–40.82) 42.24 (41.08–43.39) 1.30 (0.96–1.77) 28.10 (26.03–30.28) 45.29 (43.55–47.06) 1.75 (1.12–2.72) 35.70 (34.43–36.98) 43.17 (42.21–44.14) 1.42 (1.10–1.83)
Oslo Social Support Scalea,b,c,e
 Poor support 38.44 (37.03–39.86) 44.13 (43.06–45.20) 1.26 (1.08–1.47) 33.05 (31.00–35.20) 49.46 (47.68–51.26) 1.98 (1.58–2.49) 36.83 (35.67–38.01) 45.54 (44.63–46.46) 1.43 (1.26–1.63)
 Moderate support 44.12 (42.22–46.02) 49.78 (48.08–51.47) 1.25 (0.97–1.62) 32.33 (29.36–35.39) 50.17 (47.59–52.84) 2.10 (1.52–2.92) 41.05 (39.44–42.67) 49.89 (48.46–51.31) 1.43 (1.16–1.76)
 Strong support 24.74 (18.47–32.52) 46.93 (39.96–53.67) 2.69 (0.73–9.90) 48.58 (36.21–62.06) 42.54 (33.25–52.31) 0.78 (0.23–1.91) 31.38 (25.50–38.35) 45.46 (39.82–51.00) 1.82 (0.68–4.87)
Smokinga,e
 Yes 43.96 (42.24–45.69) 46.07 (44.44–47.70) 1.09 (0.84–1.40) 33.36 (30.59–36.16) 52.57 (49.46–55.66) 2.21 (1.43–3.41) 41.24 (39.76–42.71) 47.48 (46.03–48.92) 1.29 (1.04–1.60)
 No 38.18 (36.76–39.62) 45.73 (44.69–46.78) 1.36 (1.18–1.57) 33.24 (31.16–35.39) 49.44 (47.82–51.04) 1.96 (1.63–2.35) 36.69 (35.52–37.89) 46.83 (45.95–47.71) 1.52 (1.35–1.70)
Vapingb,c,d,e,f
 Yes 44.15 (39.72–48.67) 58.96 (54.66–63.14) 1.82 (0.96–3.44) 41.46 (35.07–48.11) 59.54 (50.85–67.28) 2.07 (1.36–3.43) 43.30 (39.65–47.04) 59.08 (55.20–62.75) 1.89 (1.08–3.31)
 No 40.41 (39.28–41.56) 45.28 (44.38–46.18) 1.22 (1.07–1.39) 32.77 (31.05–34.55) 50.01 (48.54–51.46) 2.05 (1.71–2.45) 38.27 (37.31–39.23) 46.60 (45.83–47.36) 1.41 (1.26–1.57)
Alcohol consumptiona,b,c,e,f
 More than once a month 46.88 (45.07–48.69) 49.43 (47.46–51.40) 1.11 (0.87–1.41) 36.77 (33.95–39.70) 53.74 (50.24–57.16) 1.99 (1.39–2.87) 44.15 (42.62–45.70) 50.48 (48.78–52.20) 1.29 (1.05–1.57)
 Once a month or less 36.75 (35.31–38.21) 45.08 (44.05–46.10) 1.41 (1.19–1.67) 31.28 (29.12–33.53) 50.91 (49.24–52.55) 2.28 (1.80–2.88) 35.19 (33.98–36.41) 46.71 (45.84–47.58) 1.61 (1.40–1.86)
Physical activitya,b,c,d,e,f
 Low physical activity 36.51 (35.04–37.99) 41.20 (40.08–42.33) 1.22 (1.02–1.45) 29.42 (27.38–31.56) 46.64 (44.87–48.42) 2.09 (1.72–2.55) 34.32 (33.12–35.54) 42.79 (41.84–43.75) 1.43 (1.25–1.64)
 Moderate physical activity 43.09 (40.24–45.96) 48.81 (46.62–50.97) 1.26 (0.94–1.68) 39.16 (34.64–43.57) 49.79 (46.4–53.35) 1.54 (0.91–2.62) 41.98 (39.56–44.39) 49.08 (47.25–50.94) 1.33 (1.03–1.72)
 High physical activity 46.44 (44.43–48.43) 54.87 (53.10–56.64) 1.40 (1.06–1.84) 38.83 (35.35–42.43) 61.73 (58.5–64.88) 2.54 (1.59–4.05) 44.66 (42.91–46.41) 56.43 (54.88–57.98) 1.60 (1.27–2.03)

Note: 1st quintile contains the lowest values and the 5th quintile the highest values. European Health Interview Survey Wave 3 (2018–2020). Inactive, retirees, students, and those performing domestic tasks, carrying out compulsory service, or unable to work for health reasons.  = according to the PHQ-8; ∗∗ = does not include data from Malta.

Abbreviations: EU, European Union; OR, odds ratio.

aStatistically significant self-medication differences in men with recognized depression.

bStatistically significant self-medication differences in women with recognized depressed.

cStatistically significant self-medication differences in men with depression symptoms.

dStatistically significant self-medication differences in women with depression symptoms.

eStatistically significant self-medication differences in men for both groups.

fStatistically significant self-medication differences in women for both groups.