Skip to main content
. 2025 Aug 15;2025:4661541. doi: 10.1155/da/4661541

Table 3.

Self-medication prevalence by sex in depressed and noninstitutionalized residents aged 15 and over in the European Union according to health variables.

Independent variables Recognized depression Depression symptoms Both groups
Male Female OR female Male Female OR female Male Female OR female
Medication availability clustera,b,c,d,e,f
 Pharmacy-only 32.66 (30.09–35.27) 37.45 (35.58–39.30) 1.23 (1.04–1.46) 47.41 (41.39–53.18) 61.40 (56.73–65.91) 1.76 (1.34–2.30) 35.29 (32.91–37.70) 40.85 (39.12–42.62) 1.26 (1.09–1.47)
 Nonpharmacy 45.42 (43.42–47.43) 52.28 (50.68–53.85) 1.32 (1.16–1.49) 37.30 (34.63–40.01) 51.28 (49.19–53.38) 1.77 (1.49–2.09) 42.63 (41.02–44.24) 51.91 (50.64–53.17) 1.45 (1.31–1.61)
 Limited nonpharmacy 40.09 (38.58–41.61) 45.06 (43.81–46.32) 1.22 (0.96–1.55) 27.39 (25.16–29.65) 46.09 (43.98–48.22) 2.26 (1.57–3.25) 36.62 (35.37–37.91) 45.33 (44.25–46.41) 1.43 (1.18–1.74)
Long-standing health problema,b,e
 Yes 38.78 (37.55–40.01) 46.21 (45.26–47.16) 1.36 (1.17–1.56) 34.01 (32.06–35.98) 49.51 (47.85–51.16) 1.90 (1.53–2.35) 37.49 (36.45–38.53) 47.04 (46.21–47.86) 1.48 (1.31–1.67)
 No 47.27 (44.81–49.78) 43.23 (40.97–45.47) 0.85 (0.61–1.18) 30.99 (27.82–34.41) 50.77 (47.96–53.63) 2.29 (1.60–3.29) 41.93 (39.91–43.94) 46.18 (44.43–47.97) 1.19 (0.92–1.53)
Self-perceived healtha,b,d,e,f
 Very good/good 43.66 (41.70–45.63) 48.25 (46.63–49.89) 1.20 (0.94–1.53) 34.18 (30.98–37.37) 50.57 (47.79–53.32) 1.97 (1.35–2.86) 41.23 (39.54–42.9) 48.85 (47.45–50.25) 1.36 (1.11–1.66)
 Fair 37.64 (35.87–39.49) 46.85 (45.51–48.20) 1.46 (1.19–1.79) 35.32 (32.35–38.44) 51.63 (49.25–54.02) 1.95 (1.38–2.76) 37.05 (35.50–38.61) 48.01 (46.84–49.18) 1.57 (1.32–1.87)
 Bad/very bad 40.70 (38.78–42.67) 41.45 (39.80–43.08) 1.03 (0.81–1.31) 30.84 (28.30–33.46) 47.51 (45.23–49.86) 2.03 (1.59–2.59) 37.40 (35.85–38.98) 43.51 (42.17–44.85) 1.29 (1.07–1.55)
Use of prescribed medicinea,b,e,f
 Yes 39.80 (38.61–41.00) 45.46 (44.55–46.38) 1.26 (1.10–1.45) 33.64 (31.82–35.49) 49.65 (48.15–51.16) 1.94 (1.59–2.38) 38.06 (37.06–39.07) 46.60 (45.82–47.38) 1.42 (1.27–1.59)
 No 45.41 (42.52–48.25) 49.08 (46.07–52.18) 1.16 (0.79–1.70) 31.33 (27.23–35.57) 52.53 (47.92–56.83) 2.42 (1.61–3.65) 41.32 (38.98–43.75) 50.18 (47.64–52.69) 1.40 (1.06–1.93)
Visit to a general practitioner or family doctor∗∗a,c,e
 Yes 37.85 (36.58–39.12) 45.58 (44.62–46.56) 1.37 (1.19–1.59) 34.86 (32.82–36.96) 49.20 (47.55–50.83) 1.81 (1.46–2.24) 37.06 (35.97–38.14) 46.52 (45.69–47.36) 1.47 (1.31–1.66)
 No 48.23 (46.08–50.43) 46.33 (44.27–48.39) 0.93 (0.68–1.25) 30.09 (27.29–33.03) 52.16 (49.28–55.05) 2.53 (1.80–3.57) 42.32 (40.58–44.11) 48.31 (46.63–49.99) 1.27 (1.00–1.61)
Visit to a medical or surgical specialist∗∗b,d,f
 Yes 40.73 (39.37–42.12) 46.99 (45.97–48.01) 1.29 (1.10–1.51) 34.23 (32.14–36.42) 54.79 (53.03–56.50) 2.32 (1.85–2.92) 38.92 (37.77–40.09) 48.98 (48.09–49.85) 1.51 (1.32–1.71)
 No 40.51 (38.65–42.36) 41.98 (40.27–43.73) 1.06 (0.84–1.35) 31.73 (29.08–34.53) 39.89 (37.43–42.35) 1.43 (1.05–1.93) 37.93 (36.39–39.47) 41.30 (39.89–42.72) 1.15 (0.95–1.39)
Visit to a psychologist, psychotherapist, or psychiatrist∗∗b,d,e,f
 Yes 40.37 (38.68–42.06) 50.20 (48.89–51.50) 1.49 (1.22–1.82) 35.86 (31.09–40.82) 57.64 (54.11–61.13) 2.43 (2.01–2.99) 39.90 (38.32–41.52) 51.08 (49.86–52.31) 1.57 (1.30–1.89)
 No 40.65 (39.20–42.11) 42.00 (40.82–43.17) 1.06 (0.88–1.26) 32.95 (31.16–34.75) 48.37 (46.82–49.94) 1.91 (1.57–2.32) 37.76 (36.62–38.89) 44.34 (43.40–45.29) 1.31 (1.15–1.50)
Unmet need for health care due to waiting lists∗∗a,b,c,d,e,f
 Yes 44.75 (42.64–46.86) 51.60 (50.01–53.16) 1.31 (1.02−1.69) 39.64 (36.07–43.37) 56.13 (53.49–58.68) 1.95 (1.31–2.88) 43.51 (41.68–45.34) 52.80 (51.47–54.16) 1.45 (1.17–1.79)
 No 37.33 (35.93–38.77) 42.52 (41.40–43.66) 1.24 (1.05–1.47) 31.63 (29.53–33.75) 47.85 (46.00–49.74) 1.98 (1.60–2.46) 35.66 (34.48–36.85) 43.97 (43.01–44.95) 1.41 (1.23 (1.62)
 No need for health care 46.23 (43.16–49.29) 47.14 (44.33–50.04) 1.03 (0.82–1.25) 30.72 (26.63–35.05) 44.99 (40.96–49.16) 1.84 (1.06–3.21) 41.41 (38.93–43.95) 46.44 (44.14–48.83) 1.23 (0.90–1.67)
Unmet need for health care due to distance or transportation problems∗∗a,b,e,f
 Yes 55.50 (51.74–59.10) 52.71 (49.59–55.75) 0.89 (0.53–1.50) 37.88 (33.13–43.09) 53.31 (48.85–57.70) 1.87 (1.23–2.21) 49.47 (46.48–52.49) 52.90 (50.34–55.40) 1.15 (0.75–1.74)
 No 38.44 (37.21–39.68) 44.70 (43.74–45.67) 1.29 (1.12–1.49) 33.32 (31.39–35.29) 49.73 (48.11–51.37) 1.98 (1.62–2.41) 37.05 (36.01–38.09) 46.02 (45.19–46.86) 1.45 (1.28–1.63)
 No need for health care 43.22 (40.08–46.45) 48.93 (46.11–51.74) 1.25 (1.02–1.59) 29.99 (25.64–34.55) 48.28 (44.37–52.33) 2.18 (1.36–3.48) 39.20 (36.60–41.85) 48.71 (46.44–51.03) 1.47 (1.11–1.96)
Unmet need for health care due to inability to afford medical examination or treatment∗∗a,b,c,d,e,f
 Yes 50.41 (46.69–54.01) 52.14 (49.57–54.64) 1.07 (0.71–1.61) 37.38 (32.40–42.89) 58.05 (54.26–61.78) 2.32 (1.50–3.58) 46.32 (43.32–49.38) 53.95 (51.82–56.03) 1.36 (0.98–1.87)
 No 37.99 (36.70–39.29) 44.68 (43.65–45.72) 1.32 (1.13–1.54) 33.95 (31.87–36.08) 51.04 (49.26–52.84) 2.02 (1.61–2.55) 36.92 (35.82–38.03) 46.29 (45.40–47.19) 1.47 (1.29–1.67)
 No need for health care 47.46 (44.66–50.23) 47.02 (44.59–49.48) 0.98 (0.69–1.40) 29.25 (25.73–33.08) 42.69 (39.29–46.16) 1.80 (1.10–2.95) 41.58 (39.33–43.86) 45.58 (43.60–47.59) 1.18 (0.88–1.58)
Unmet need for health care due to inability to afford prescribed medicines∗∗a,c,d,e
 Yes 49.05 (45.23–52.82) 48.66 (46.01–51.33) 0.98 (0.62–1.55) 47.16 (41.73–52.66) 50.60 (46.38–54.69) 1.15 (0.69–1.90) 48.44 (45.36–51.60) 49.22 (46.97–51.46) 1.03 (0.73–1.46)
 No 38.74 (37.48–39.99) 45.53 (44.53–46.53) 1.32 (1.14–1.53) 31.44 (29.45–33.47) 51.93 (50.24–53.64) 2.35 (1.89–2.93) 36.82 (35.76–37.90) 47.18 (46.32–48.04) 1.53 (1.35–1.73)
 No need for health care 47.92 (44.71–51.07) 47.64 (44.74–50.67) 0.99 (0.65–1.52) 32.70 (28.7–37.06) 43.58 (39.58–47.62) 1.59 (0.93–2.71) 42.78 (40.24–45.37) 46.22 (43.84–48.62) 1.15 (0.82–1.61)
Unmet need for health care due to inability to afford mental health care∗∗a,b,d,e,f
 Yes 45.46 (42.05–48.85) 54.55 (51.83–57.18) 1.44 (0.95–2.18) 41.24 (33.68–49.32) 60.49 (54.81–66.27) 2.18 (1.09–4.34) 44.81 (41.69–47.94) 55.58 (53.13–57.99) 1.54 (1.06–2.22)
 No 39.90 (38.52–41.27) 45.14 (44.05–46.24) 1.24 (1.05–1.46) 32.92 (30.48–35.36) 51.92 (49.82–54.05) 2.20 (1.65–2.94) 38.32 (37.13–39.53) 46.58 (45.61–47.56) 1.40 (1.21–1.62)
 No need for health care 39.98 (37.65–42.34) 44.88 (43.00–46.75) 1.22 (0.94–1.59) 32.94 (30.35–35.50) 48.31 (46.16–50.52) 1.90 (1.45–2.49) 36.93 (35.19–38.67) 46.34 (44.92–47.76) 1.47 (1.22–1.78)

Note: European Health Interview Survey Wave 3 (2018–2020).  = according to the PHQ-8; ∗∗ = in the past 12 months.

Abbreviation: OR, odds ratio.

aStatistically significant self-medication differences in men with recognized depression.

bStatistically significant self-medication differences in women with recognized depressed.

cStatistically significant self-medication differences in men with depression symptoms.

dStatistically significant self-medication differences in women with depression symptoms.

eStatistically significant self-medication differences in men for both groups.

fStatistically significant self-medication differences in women for both groups.