Table 3.

Results of multivariate analysis for survival

Survival	Variables	HR	95% CI	p-value
OS (from diagnosis)	Tumor volume (< vs. ≥ 59 cc)	0.4	[0.1–1]	0.05
	Re-irradiation (yes vs. no)	0.2	[0.07–0.5]	0.007*
	Time-to-progression (≥ vs. < 8 months)	0.2	[0.1–0.7]	0.002*
PFS	Tumor volume (< vs. ≥ 59 cc)	0.2	[0.1–0.7]	0.01*
	Concurrent CHT (yes vs. no)	0.5	[0.2–1.4]	0.02*
OS (after progression)	Tumor volume (< vs. ≥ 59 cc)	0.4	[0.2–1.1]	0.08
	Re-irradiation (yes vs. no)	0.4	[0.1–0.9]	0.04*

CI confidence interval, CHT chemotherapy, HR hazard ratio, OS overall survival, PFS progression-free survival

*Statistically significant p-value