Table 2.
Average adjusted food group and micronutrient intakes for survivors of cancer post-neurotoxic chemotherapy predicting the odds of chemotherapy-induced peripheral neuropathy (CIPN) adjusting for caloric intake, age, race, sex, BMI, and food security per 1,000 kilocalories
| Dietary Component (N=136) |
Average amount of intake by CIPN status | Mean adjusted difference p-value |
OR (95% CI)b |
OR p-value |
|
|---|---|---|---|---|---|
| CIPN Presenta (n=76) |
No CIPNa (n=60) |
Odds of having CIPN | |||
| Food Groups | |||||
| Dark Green Vegetables (cups/day) | 0.19 (0.14, 0.24) | 0.19 (0.13, 0.25) | 0.98 |
1.53 (0.44, 5.32) |
0.50 |
| Red and Orange Vegetables (cups/day) | 0.07 (0.04, 0.09) | 0.08 (0.04, 0.11) | 0.77 |
3.11 (0.35, 27.68) |
0.31 |
| Tomatoes⏶ (cups/day) | 0.18 (0.15, 0.21) | 0.21 (0.17, 0.26) | 0.18 |
0.10 (0.01, 1.14) |
0.06 |
| Other Vegetables (cups/day) | 0.24 (0.20, 0.29) | 0.26 (0.21, 0.31) | 0.65 |
0.67 (0.14, 3.23) |
0.62 |
| Whole Grains (oz/day) | 0.61 (0.46, 0.75) | 0.57 (0.41, 0.72) | 0.73 |
0.83 (0.44, 1.56) |
0.55 |
| Refined Grains*⏶ (oz/day) | 1.68 (1.48, 1.88) | 1.32 (1.14, 1.49) | 0.01 |
2.05 (1.22, 3.46) |
<0.01 |
| Fruit (cups/day) | 0.76 (0.61, 0.90) | 0.80 (0.62, 0.97) | 0.74 |
0.90 (0.52, 1.55) |
0.71 |
| Red Meat (oz/day) | 0.17 (0.12, 0.22) | 0.15 (0.10, 0.20) | 0.70 |
0.83 (0.14, 4.76) |
0.83 |
| Poultry (oz/day) | 0.41 (0.32, 0.51) | 0.54 (0.39, 0.69) | 0.17 |
0.66 (0.32, 1.34) |
0.25 |
| Fish⏶ (oz/day) | 0.15 (0.09, 0.21) | 0.22 (0.12, 0.31) | 0.30 |
0.21 (0.06, 0.75) |
0.02 |
| Egg*⏶ (oz/day) | 0.16 (0.12, 0.21) | 0.26 (0.18, 0.33) | 0.04 |
0.06 (0.01, 0.34) |
<0.01 |
| Nuts/Seeds (oz/day) | 0.52 (0.35, 0.68) | 0.39 (0.25, 0.54) | 0.30 |
1.14 (0.85, 1.52) |
0.40 |
| Dairy (cups/day) | 0.76 (0.63, 0.89) | 0.68 (0.55, 0.80) | 0.39 |
1.49 (0.63, 3.53) |
0.37 |
| Legumes* (cups/day) | 0.05 (0.03, 0.06) | 0.09 (0.05, 0.12) | 0.05 |
0.18 (0.00, 16.74) |
0.46 |
| Micronutrients | |||||
| Vitamin A (IU/day) |
6702.07 (5609.32, 7794.82) |
5414.70 (4405.73, 6423.67) |
0.11 |
1.00 (1.00, 1.00) |
0.11 |
| Vitamin D (IU/day) |
122.61 (103.78, 141.44) |
135.91 (112.05, 159.77) |
0.42 |
1.00 (0.99, 1.00) |
0.24 |
| Vitamin E (IU/day) |
10.50 (9.29, 11.71) |
10.59 (9.20, 11.98) |
0.93 |
1.01 (0.96, 1.07) |
0.71 |
| Vitamin K (mcg/day) |
108.34 (89.09, 127.60) |
94.84 (75.58, 114.11) |
0.37 |
1.00 (1.00, 1.01) |
0.11 |
| Thiamin* (mg/day) |
0.81 (0.77, 0.86) |
0.75 (0.70, 0.80) |
0.09 |
3.47 (0.42, 28.82) |
0.25 |
| Riboflavin (mg/day) |
1.11 (1.03, 1.18) |
1.15 (1.07, 1.24) |
0.45 |
0.83 (0.33, 2.06) |
0.68 |
| Niacin (mg/day) |
12.74 (11.78, 13.71) |
13.28 (12.13, 14.43) |
0.51 |
1.00 (0.95, 1.04) |
0.85 |
| Pantothenic Acid (mg/day) |
3.58 (3.21, 3.95) |
3.73 (3.29, 4.17) |
0.62 |
1.01 (0.94, 1.09) |
0.77 |
| Vitamin B6 (mg/day) |
1.15 (1.05, 1.25) |
1.20 (1.09, 1.32) |
0.53 |
0.94 (0.61, 1.44) |
0.78 |
| Folate (mcg/day) |
151.82 (138.99, 164.65) |
155.28 (140.28, 170.28) |
0.75 |
1.00 (0.99. 1.01) |
0.82 |
| Vitamin B12 (mcg/day) |
2.42 (2.13, 2.71) |
2.60 (2.24, 2.96) |
0.47 |
0.96 (0.84, 1.11) |
0.61 |
| Vitamin C (mg/day) |
83.52 (71.40, 95.64) |
74.91 (62.48, 87.33) |
0.36 |
1.00 (1.00, 1.01) |
0.30 |
| Magnesium (mg/day) |
197.57 (184.97, 210.17) |
192.22 (178.21, 206.23) |
0.60 |
1.00 (1.00, 1.01) |
0.33 |
| Selenium*⏶ (mcg/day) |
55.58 (53.29, 57.86) |
60.13 (57.31, 62.95) |
0.02 |
0.96 (0.92, 1.00) |
0.03 |
| Iron (mg/day) |
7.78 (7.25, 8.31) |
7.30 (6.72, 7.87) |
0.26 |
1.08 (0.91, 1.28) |
0.38 |
| Copper (mg/day) |
0.85 (0.80, 0.91) |
0.82 (0.76, 0.89) |
0.57 |
1.67 (0.30, 9.19) |
0.56 |
| Zinc (mg/day) |
5.97 (5.64, 6.30) |
6.16 (5.77, 6.54) |
0.50 |
0.89 (0.70, 1.13) |
0.33 |
| Calcium (mg/day) |
582.53 (531.05, 634.01) |
555.10 (499.04, 611.17) |
0.51 |
1.00 (1.00, 1.00) |
0.28 |