Table 7.
Secondary outcome – Adverse Events - Trismus
| Comparison | Number of sites (primary studies) | Measure of effect | Effect model | Direction of effect | Follow up | Heterogeneity |
|---|---|---|---|---|---|---|
| Envelope vs triangular flap* | 103 vs 104 (4) | SMD= –0.16; 95% CI (–0.72, 0.41) | Random | No difference | 2 days | I2=73% |
| Envelope vs triangular flap* | 65 vs 65 (3) | SMD= –0.12; 95% CI (–0.47, 0.22) | Fixed | No difference | 3 days | I2=0 |
| Envelope vs triangular flap* | 137 vs 137 (5) | MD= 0.28; 95% CI (–0.41, 0.98) | Random | No difference | 7 days | I2=83% |
| Envelope vs triangular flap** | 107 vs 100 (3) | MD= –1.02; 95% CI (–4.25, 2.22) | Random | No difference | 7 days | I2= 67% |
| Envelope vs triangular flap** | 39 vs 39 (2) | SMD= 0.25; 95% CI (–0.75, 1.26) | Random | No difference | 14 days | I2= 80% |
| PRF vs Spontaneous healing* | 45 vs 45 (2) | SMD= 0.20; 95% CI (–0.56, 0.95) | Random | No difference | 7 days | I2=69% |
| PRF vs Spontaneous Healing* | 105 vs 105 (3) | SMD= –0.50; 95% (–0.78, –0.22) | Fixed | Favors PRF | 1 day | I2= 17.1% |
| PRF vs Spontaneous Healing* | 60 vs 60 (2) | SMD= –0.34; 95% CI (–0.71, 0.02) | Fixed | No difference | 3 days | I2= 0 |
| PRF vs Spontaneous Healing* | 155 vs 155 (5) | SMD= –0.26; 95% CI (–0.48, –0.03) | Fixed | Favors PRF | 7 days | I2= 18.7% |
| HyA application vs Spontaneous Healing* | 64 vs 64 (3) | MD= 1.31; 95% CI (–0.65, 3.26) | Random | No difference | 2–3 days | I2= 25.86% |
| HyA application vs Spontaneous Healing* | 140 vs 134 (5) | MD= 1.08; 95% CI (–0.97, 3.12) | Random | No difference | 7 days | I2= 55.99% |
PRF platelet rich fibrin, A-PRF advanced - platelet rich fibrin, MD mean difference, SMD standardized mean difference, CI Confidence Interval, HyA hyaluronic acid
*Outcome measure: Postoperative interincisal distance
**Outcome measure: Change in interincisal distance