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. 2025 Aug 22;11:55. doi: 10.1186/s40729-025-00643-5

Table 1.

Summary of the main characteristics and outcomes of the included studies

Author Year Type of study Nº of patients Nº of implants Type of mesh Bone Graft Bone gain Vertical (mm) Bone gain horizontal (mm) Membrane exposure (%) Other complications (%) Follow-up (months)
Chiapasco et al. [17] 2021 RS 41 106 CAD/CAM MIX: Auto + DBBM 4.78 ± 1.88 6.35 ± 2.10 20.7 2.5 10.6 ± 6.5
Corinadelsi et al. [19] 2009 RS 24 56 Conventional Auto 5.45 ± 1.16 NA 14. 8 NA 39–96
Cucchi et al. [28] 2017 RCT 20 108 Conventional MIX: Auto + ALO 4.1 ± 1.0 NA 21.1 15.8 6–9
Dellavia et al. [26] 2021 CS 20 48 CAD/CAM MIX: Auto + DBBM 5.20 ± 1.76 6.8 ± 2.51 15 NA 9
El Chaar et al. [20] 2019 RS 39 63 Conventional Allograft 6.37 6.42 46.15 10.25 18–48
Gomes et al. [31] 2016 RS 25 40 Conventional DBBM NA 3.67 ± 0.89 24 48 12
Hartmann et al. [33] 2020 RS 55 98 CAD/CAM MIX: Auto + DBBM NA NA 25 NA 6.53 ± 2.7
Her et al. [10] 2012 RS 26 69 Conventional DBBM NA NA 26 NA 6–24
Jung et al. [34] 2014 PS 10 12 CAD/CAM MIX: Auto + ALO NA NA 3 NA 12
Lizio et al. [13] 2016 PS 24 88 Conventional MIX: Auto + DBBM NA NA 58.82 11.76 6–12
Louis et al. [21] 2008 RS 44 174 Conventional MIX: Auto + DBBM 13.5 ± 1.7 NA 52.3 NA 3-6-9
Miyamoto et al. [22] 2012 RS 27 87 Conventional Auto 5.4 ± 3.4 3.7 ± 2.0 40.7 66.66 47.5
Poli et al. [32] 2014 RS 13 20 Conventional MIX: Auto + DBBM NA NA 7.69 NA 88
Rocuzzo et al. [24] 2007 PS 12 NA Conventional Autogenous Block 5.7 ± 1.5 3.4 33.3 NA 4–6
Sagheb et al. [18] 2017 PS 17 44 CAD/CAM MIX: Auto + DBBM 6.5 ± 1.7 5.5 ± 1.9 33 NA 6–12
Torres et al. [25] 2010 RCT 30 97 Conventional Anorganic bovine Bone (ABB) 3.3 ± 0.2 3.9 ± 0.2 20 NA 24
Nan et al. [27] 2023 RS 59 80 CAD/CAM MIX: Auto + DBBM 5.01 ± 2.83 5.22 ± 3.19 32.8 NA 12
Li et al. [30] 2023 RS 36 57 CAD/CAM MIX: Auto + DBBM 2.38 ± 2.69 5.37 ± 2.01 16.67 NA 6–8
Cucchi et al. [12] 2021 RCT 30 71 CAD/CAM MIX: Auto + DBBM 5.55 ± 2.38 NA 23.3 6.6 6
Pellegrino et al. [28] 2024 PS 16 NA CAD/CAM MIX: Auto + DBBM 5,89 ± 0.45 9.52 ± 0.65 12.5 NA 8
Chen et al. [16] 2023 RS 30 NA CAD/CAM MIX: Auto + DBBM 5.02 ± 1.42 NA 30 0 6
Hernández-Alfaro et al. [29] 2024 PS 10 NA CAD/CAM MIX: Auto + DBBM 5.87 ± 1.6 5.64 ± 2.1 20 0 6

Abbreviations: RCT, randomized controlled trial; RS, retrospective study; PS, prospective study; CS, case series; Auto, autologous bone; DBBM, deproteinized bovine bone mineral; ALO, allograft; ABB, anorganic bovine bone; CAD/CAM, computer-aided design/computer-aided manufacturing; NA, not available