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. 2025 Jun 30;41(9):1136–1143. doi: 10.1007/s12055-025-01965-0

Table 2.

Factors associated with post-operative moderate to severe TR after mitral valve replacement

Variables Moderate to severe TR (n = 59) Mild TR (n = 83) P-value
Age (mean ± SD) 46.34 ± 12.06 42.66 ± 11.89 0.073
Gender (%)
Male 20 (33.9) 29 (34.9) 0.898
Female 39 (66.1) 54 (65.1)
Duration of symptoms in months (median, IQR) 24 (12–48) 12 (6–48) 0.064
NYHA (%)
1 0 1 (1.2) 0.864
2 48 (81.4) 63 (75.9)
3 10 (16.9) 18 (21.7)
4 1 (1.7) 1 (1.2)
ECG (%)
Sinus rhythm 9 (15.3) 30 (36.1) 0.006
Atrial fibrillation 50 (84.7) 53 (63.9)
LA size (%)
≤ 6 mm 46 (78) 64 (77.1) 0.904
> 6 mm 13 (22) 19 (22.90)
Mitral lesion (%)
Mitral stenosis 33 (55.9) 33 (39.8) 0.160
Mitral regurgitation 10 (16.9) 18 (21.7)
Mixed lesion 16 (27.1) 32 (38.6)
LVEF
≤ 50% 4 (6.8) 4 (4.8) 0.719
> 50% 55 (93.2) 79 (95.2)
TAP (%)
Done 9 (15.3) 32 (38.6) 0.003
Not done 50 (84.7) 51 (61.4)
TAPSE (%)
≥ 17 mm 29 (49.2) 51 (61.4) 0.146
< 17 mm 30 (50.8) 32 (38.6)
Pulmonary artery systolic pressure (%)
≤ 40 mmHg 12 (20.3) 10 (12) 0.178
> 40 mmHg 47 (79.7) 73 (88)
Tricuspid annulus size (TAP not done) (n = 101) (%)
< 35 mm 37 (74) 39 (76.5) 0.774
≥ 35 mm 13 (26) 12 (23.5)
RV-PA coupling (%)
< 0.31 25 (42.4) 39 (47) 0.586
≥ 0.31 34 (57.6) 44 (53)

TR tricuspid regurgitation, NYHA New York Heart Association, ECG electrocardiogram, LA left atrium, LVEF left ventricular ejection fraction, TAP tricuspid annuloplasty, TAPSE tricuspid annular plane systolic excursion, RV-PA coupling right ventricle/pulmonary artery coupling