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Summary of validation studies for mngs in diagnosing CNE
| Study | Sample Size | Sensitivity | Specificity | Main Findings | Reference |
|---|---|---|---|---|---|
| Wu et al. (2024) | 195 | 89.8% | 76.3% | High diagnostic yield, reduced false negatives | [110] |
| Chen et al. (2024) | 2325 | 87% | 59% | Comprehensive pathogen detection, improved clinical prognosis | [109] |
| Diao et al. (2023) | 69 | 95.18% | 91.30% | Enhanced detection of rare pathogens, guided targeted therapy | [111] |
