Table 2.
Mean ± SD vitamin D (VD) levels in relation to main characteristics of patients with Crohn’s disease (CD)
| Patient characteristics | VD levels (ng/ml) | P |
|---|---|---|
|
Age, < 40 years (n = 89) ≥ 40 years (n = 33) |
19.7 ± 6.9 16.1 ± 8.3 |
0.017 |
|
Gender, males (n = 78) females (n = 44) |
19.3 ± 8.1 17.6 ± 6.3 |
0.215 |
|
Body mass index, ≤ 25 kg/m2 (n = 67) > 25 kg/m2 (n = 55) |
19.4 ± 6.7 17.9 ± 8.3 |
0.280 |
|
Smoking, yes (n = 34) no (n = 88) |
16.9 ± 8.5 19.4 ± 6.9 |
0.095 |
|
Disease duration, ≤ 3 years (n = 58) > 3 years (n = 64) |
18.3 ± 7.9 19.1 ± 7.1 |
0.598 |
|
Harvey-Bradshaw Index, < 5 (n = 108) ≥ 5 (n = 14) |
19.4 ± 7.5 13.9 ± 5.4 |
0.009 |
|
C-Reactive Protein, ≤ 5 mg/l (n = 83) > 5 mg/l (n = 39) |
19.9 ± 7.6 16.2 ± 6.8 |
0.011 |
|
Stool calprotectin, ≤ 180 μg/mg (n = 47) > 180 μg/mg (n = 41) |
20.4 ± 7.9 17.1 ± 6.7 |
0.038 |
|
Location, L1 (n = 54) L2 (n = 20) L3 (n = 48) |
18.5 ± 8.2 18.1 ± 7.7 19.1 ± 6.6 |
0.855 |
|
L4, yes (n = 29) no (n = 93) |
18.3 ± 6.1 18.9 ± 7.9 |
0.751 |
|
Behaviour, B1 (n = 70) B2 (n = 43) B3 (n = 9) |
18.5 ± 7.2 18.2 ± 7.7 23.4 ± 7.7 |
0.146 |
|
Perianal disease, yes (n = 27) no (n = 95) |
20.5 ± 8 18.2 ± 7.3 |
0.157 |
|
Endoscopic activity, yes (n = 63) no (n = 27) |
17.9 ± 7.3 18.3 ± 6.9 |
0.788 |
|
Histologic activity, yes (n– = 61) nο (n = 25) |
17.2 ± 6.9 18.1 ± 6.8 |
0.599 |
|
Treatment, n (%) Biologic agent ± other agents (n = 72) Azathioprine without biologic (n = 11) Steroids ± mesalazine (n = 8) Mesalazine only (n = 10) |
18.7 ± 7.3 18.3 ± 8.3 17.8 ± 4.1 16.8 ± 7.8 |
0.878 |