Table 3.

Allele and haplotype distribution between groups

Verteilung der Allele und Haplotypen zwischen den Gruppen

Chromosome	Gene	SNPs	Allele/Haplotypes	Frequency		p-value
				Orthognathic mandible	Retrognathic mandible
4	EGF	rs4444903	G	0.477	0.305	0.008*
		rs2237051	A	0.488	0.376	0.096
		rs4444903|rs2237051	G|A	0.387	0.222	0.007*
			A|A	0.113	0.154	0.382
			G|G	0.089	0.089	0.988
			A|G	0.410	0.534	0.071
7	EGFR	rs2227983	A	0.352	0.253	0.109
		rs763317	G	0.511	0.423	0.191
		rs2227983|rs763317	A|G	0.187	0.098	0.053
			G|G	0.336	0.317	0.769
			A|A	0.165	0.155	0.838
			G|A	0.312	0.429	0.075

Frequencies between the major alleles were compared by chi-square test and between the expected number of haplotypes by Fisher exact test

EGF epidermal growth factor, EGFR epidermal growth factor receptor

*p < 0.05