Table 2.
Demographics and clinicopathological characteristics of patients with esophageal carcinoma.
| Characteristics | All patients (n = 1542) | Training cohort (N = 1116) | Validation cohort (N = 426) | P value | |||
|---|---|---|---|---|---|---|---|
| Number | % | Number | % | Number | % | ||
| Sex | |||||||
| Male | 1288 | 83.5 | 931 | 83.4 | 357 | 83.8 | 0.857 |
| Female | 254 | 16.5 | 185 | 16.6 | 69 | 16.2 | |
| Race | |||||||
| White | 1274 | 82.6 | 923 | 82.7 | 351 | 82.4 | 0.885 |
| Unwhite | 268 | 17.4 | 193 | 17.3 | 75 | 17.6 | |
| Age | |||||||
| < 65 years | 877 | 56.9 | 630 | 56.5 | 247 | 58.0 | 0.588 |
| ≥ 65 years | 665 | 43.1 | 486 | 43.5 | 179 | 42.0 | |
| Marriage | |||||||
| Married | 861 | 55.8 | 627 | 56.2 | 234 | 54.9 | 0.658 |
| Unmarried | 681 | 44.2 | 489 | 43.8 | 192 | 45.1 | |
| Chemotherapy | |||||||
| None | 478 | 31.0 | 351 | 31.5 | 127 | 29.8 | 0.534 |
| Yes | 1064 | 69.0 | 765 | 68.5 | 299 | 70.2 | |
| Radiotherapy | |||||||
| None | 771 | 50 | 561 | 50.3 | 210 | 49.3 | 0.733 |
| Yes | 771 | 50 | 555 | 49.7 | 216 | 50.7 | |
| Histology | |||||||
| Adenocarcinoma | 1032 | 66.9 | 751 | 67.3 | 281 | 66.0 | 0.619 |
| Non- adenocarcinoma | 510 | 33.1 | 365 | 32.7 | 145 | 34.0 | |
| Primary site | |||||||
| Cervical/Upper | 61 | 4.0 | 40 | 3.6 | 21 | 4.9 | 0.058 |
| Thoracic/middle | 279 | 18.1 | 201 | 18.0 | 78 | 18.3 | |
| Abdominal/lower | 1119 | 72.6 | 805 | 72.1 | 314 | 73.7 | |
| Overlapping | 83 | 5.4 | 70 | 6.3 | 13 | 3.1 | |
| Surgery | |||||||
| None | 1459 | 94.6 | 1054 | 94.4 | 405 | 95.1 | 0.626 |
| Yes | 83 | 5.4 | 62 | 5.6 | 21 | 4.9 | |
| Grade | |||||||
| I + II | 552 | 35.8 | 401 | 35.9 | 151 | 35.4 | 0.859 |
| III + IV | 990 | 64.2 | 715 | 64.1 | 275 | 64.6 | |
| T Stage | |||||||
| T1 | 414 | 26.8 | 295 | 26.4 | 119 | 27.9 | 0.620 |
| T2 | 84 | 5.4 | 66 | 5.9 | 18 | 4.2 | |
| T3 | 390 | 25.3 | 285 | 25.5 | 105 | 24.6 | |
| T4 | 399 | 25.9 | 291 | 26.1 | 108 | 25.4 | |
| Tx | 255 | 16.5 | 179 | 16.0 | 76 | 17.8 | |
| N Stage | |||||||
| N0 | 417 | 27.0 | 299 | 26.8 | 118 | 27.7 | 0.684 |
| N1 | 998 | 64.7 | 721 | 64.6 | 277 | 65.0 | |
| Nx | 127 | 8.2 | 96 | 8.6 | 31 | 7.3 | |
| M Stage | |||||||
| M1a | 74 | 4.8 | 51 | 4.6 | 23 | 5.4 | 0.496 |
| M1b | 1468 | 95.2 | 1065 | 95.4 | 403 | 94.6 | |
| Vital status | |||||||
| Alive | 34 | 2.2 | 24 | 2.2 | 10 | 2.3 | 0.814 |
| Death | 1508 | 97.8 | 1092 | 97.8 | 416 | 97.7 | |