Table 2.
The effects of PEG-rhG-CSF and rhG-CSF on short-term hematopoietic reconstitution.
| PEG-rhG-CSF | rhG-CSF | p value | |
|---|---|---|---|
| Median number of reinfused CD34 + cells, × 106/kg (range) | 3.6 (1.9–8.1) | 3.8 (1.49–10.5) | 0.793 |
| Median number of RBC infusions, units (range) | 0.3 (0–3.5) | 0.2 (0–4) | 0.594 |
| Median number of PLT transfusions, units (range) | 2.9 (1–8) | 1.6 (0–4) | < 0.001 |
| Median time to ANC > 0.5 × 109/L, days (range) | 11.3 (9–21) | 11.0 (9–13) | 0.324 |
| Median time to PLTc > 20 × 109/L, days (range) | 13.7 (10–24) | 11.4 (8–16) | < 0.001 |
| Duration of neutropenia, days (range) | 7.3 (5–8) | 6.8 (6–9) | 0.249 |
| Median days on parenteral antibiotics, (range) | 10.0 (5–18) | 8.8 (0–20) | 0.207 |
| Median days of hospitalization, (range) | 27.1 (20–34) | 26.4 (16–41) | 0.499 |
| Median hospitalization cost, RMB (range) | 77,126 (49,909–107,881) | 68,361 (38,532–116,275) | 0.027 |
| Number of patients who received RBC transfusions, n (%) | 4 (12.1%) | 2 (5.4%) | > 0.99 |
| Number of patients who received platelet transfusions, n (%) | 33 (100%) | 35 (94.6%) | > 0.99 |
RBC, Red blood cell; PLTc, Platelet count; ANC, Absolute neutrophil count; G-CSF, Granulocyte colony-stimulating factor.
Significant values are in italics