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. 2025 Aug 23;15:30983. doi: 10.1038/s41598-025-16817-5

Table 1.

The two-stage least squares (2SLS) method evaluated the impact of varying levels of body mass index (BMI) on lymphocyte telomere length (LTL). SE, standard error; MR2, multiple R-squared; AR2, adjusted R-squared. a, PIVW=0.06; b, PIVW=0.0002.

Subgroup Estimate SE P MR2 AR2 Wald test
Overweight (BMI 25 ~ 29.9Kg/m2)
 Intercept 5.35E-04 5.75E-04 3.62E-01 0.0271 -0.0135 0.67
 Predicted -6.77E-03 8.28E-03 4.22E-01
Obesity class I (BMI 30 ~ 34.9Kg/m2)
 Intercept 9.02E-05 4.81E-04 8.52E-01 0.1575 0.1341 6.73
 Predicted -1.20E-02 4.64E-03 1.36E-02a
Obesity class Ⅱ (BMI 35 ~ 39.9Kg/m2)
 Intercept 4.70E-04 5.11E-04 3.66E-01 0.0934 0.0621 2.99
 Predicted -6.26E-03 3.62E-03 9.46E-02
Obesity class Ⅲ (BMI > 40Kg/m2)
 Intercept 1.98E-05 8.52E-04 9.82E-01 0.5944 0.5365 10.26
 Predicted -1.14E-02 3.56E-03 1.50E-02b