Table 1.

The significant clusters of ALE analysis.

Type	Age range	Modality	Contrast	Cluster Names	x	y	z	cluster size (2*2*2 mm)	Remark
Main analysis	All	All	All	lIFG	−42	15	5	266	extending to Ins
				lMFG	−44	12	29	385	extending to IFG
	All	All	Increase	lMFG	−44	13	29	161	extending to IFG
Sub-group analysis	All	Comprehension	All	lMFG	−44	11	28	182	extending to IFG
				rMFG	43	43	18	107
	All	Production	All	lIFG	−45	20	2	129	extending to Ins
Comparison analysis	All	Comprehension > Production	All	rMFG	42	42	21	66
	All	Comprehension < Production	All	lIFG	−45	20	2	113	extending to Ins
				lIns	−37	15	12	37
				lMFG	−44	20	31	21
Sub-group analysis	All	Comprehension	Decrease	rMFG	43	44	17	123
	All	Production	Increase	lIFG	−40	12	8	202	extending to Ins
Age-effects	>=35	All	Increase	lMFG	−44	14	30	137	extending to IFG
	<35	Comprehension	Decrease	rMFG	43	46	13	149

Denotes: lMFG left middle frontal gyrus; lIFG left inferior frontal gyrus; rMFG right middle frontal gyrus; lIns left insula.