. 2025 Aug 22;15:30916. doi: 10.1038/s41598-025-12650-y

Table 9.

Serum urea, creatinine and endogenous creatinine clearance after treatment.

Metabolism-related indicators	EN1 (n=25)	EN2 (n=25)	EN3 (n=25)	EN4 (n=25)	H	P
Serum urea(mmol/L)	5.2 (4.0, 7.5)	5.4 (3.4, 8.7)	6.2 (4.9, 8.2)	6.4 (5.1, 8.5)	4.39	0.22
Creatinine (µmol/L)	59.0 (51.0, 72.0)	61.0 (50.5, 74.5)	62.0 (52.5, 70.0)	59.0 (44.5, 71.5)	0.74	0.86
Endogenous creatinine clearance (ml/mim· 1.73m²⁾	110.1 (97.1, 116.7)	106.9 (95.2, 115.1)	108.7 (94.0, 117.5)	106.5 (89.0, 113.9)	0.83	0.84

Metabolism-related indicators

EN1
(n=25)

EN2
(n=25)

EN3
(n=25)

EN4
(n=25)

Serum urea(mmol/L)

5.2

(4.0, 7.5)

5.4

(3.4, 8.7)

6.2

(4.9, 8.2)

6.4

(5.1, 8.5)

4.39

0.22

Creatinine (µmol/L)

59.0

(51.0, 72.0)

61.0

(50.5, 74.5)

62.0

(52.5, 70.0)

59.0

(44.5, 71.5)

0.74

0.86

Endogenous creatinine clearance (ml/mim· 1.73m²⁾

110.1

(97.1, 116.7)

106.9

(95.2, 115.1)

108.7

(94.0, 117.5)

106.5

(89.0, 113.9)

0.83

0.84