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. 2025 Aug 22;15:30902. doi: 10.1038/s41598-025-15614-4

Table 6.

Concentration of the selected pharmaceuticals in riverine waters and wastewater treatment plants (WWTP) in literature data.

Compounds [ng/L]
Sample location Caffeine (CAF) Ibuprofen (IBU) Carbamazepine (CBM) References
Rivers
Wisła River, Kraków, Poland 326–1198 38 40 66,67
Rudawa River, Kraków, Poland 367–626 33 58 66,67
Dłubnia River, Kraków, Poland 370 10 47 66
Wilga River, Kraków, Poland 326 67
Surface water, Poland 113–5250 4–737 28–1840 68,69
Surface water, UK 55–199  < 0.2–5044  < 1–25 70
Surface water, Germany  < 1–7100 70
Surface water, France 13–107 ND–5 ND–56 71
Surface water, Spain 12–416 6–2784 0.3–104 72
Surface water, Greece 38–72  < LOQ 92–186 73
Surface water, Nigeria  < 4–1080 6720  < 1–342 74
Surface water, South Africa 1170–60,530 74
Surface water, China 66–8571  < LOD–195 1–30 8,75
Surface water, Brazil 200–14,820  < 20–1590 54
WWTPs
Kraków WWTP influent 2334–6768 666–3070 1452–3427 66
Kraków WWTP effluent  < LOQ–1432 17–672 42–137 66
WWTP Poland influent 78,300–156,000 280–23,800 1120–2690 36,68
WWTP Poland effluent ND–364 0–110 1650–2240 36,68
WWTP Greece influent 856–6679  < LOD–1258 326–1012 73
WWTP Greece effluent 28–119  < LOD–790 172–552 73
WWTP Jordan influent 156,000 3138–3352 76
WWTP Jordan effluent 1560 2365–3020 76
WWTP Canada influent 3124 77
WWTP Canada effluent 2956 77

– lack of data.