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. 2025 Jul 18;26(16):4153–4179. doi: 10.1038/s44319-025-00516-3

Reagents and tools table

Reagent/resource Reference or source Identifier or catalog number
Experimental models

C57BL/6J

Sepp1KO (B6.Cg-Selenoptm1Rfb)

Sepp1U40S/U40S (B6.Cg-Selenoptm3.1Rfb)

Sepp1Δ240-361 (B6.Cg-Selenoptm4.1Rfb)

Sepp1fl/fl (B6.Cg-Selenoptm3.1Rfb)

LysMCre mice (B6.129P2-Lyz2tm1(cre)Ifo/J)

LysMCre/+;Sepp1fl/fl

CX3CR1gfp/+

Hill et al, 2003

Kurokawa et al, 2014

Hill et al, 2007

Hill et al, 2012

Antibodies
Anti-a7-integrin Alexa Fluor 647-conjugated AB lab, University of British Columbia AB0000538
Anti-CCL3 Santa Cruz sc-1383
Anti-CD163 Santa Cruz sc-33560
Anti-CD206 Santa Cruz sc-58987
Anti-CD31 Abcam ab7388
Anti-CD31 PE-conjugated eBioscience 12-0311-82
Anti-CD34 FITC-conjugated eBioscience 11-0341-82
Anti-CD45 eBioscience 25-0451-81
Anti-CD45 PE-Cy7-conjugated eBioscience 25-0451-82
Anti-CD64 BD PharMingen 558539
Anti-Collagen I Southern Biotech 1310-01
Anti-desmin antibody Abcam 32362
Anti-eMHC/MYH3 Santa sc-53091
Anti-F4/80 Abcam ab6640
Anti-iNOS Abcam ab3523
Anti-Ki67 Abcam 15580
Anti-laminin Sigma-Aldrich L9393
Anti-Ly6C eBioscience 12-5932-82
Anti-Ly6C antibody APC-conjugated eBioscience 17-5932-82
Anti-Pax7 (hybridoma) DSHB
Anti-PDGFRα RD systems AF1062
Anti-perilipin Abcam ab3526
Anti-Sca-1 PerCP-Cy5.5- conjugated eBioscience 45-5981-82
Cy™3 AffiniPure® Donkey Anti-Mouse IgG (H + L) Jackson ImmunoResearch 715-165-150
Alexa Fluor® 488 AffiniPure® Donkey Anti-Mouse IgG (H + L) Jackson ImmunoResearch 715-545-150
Alexa Fluor® 488 AffiniPure® Goat Anti-Rabbit IgG (H + L) Jackson ImmunoResearch 111-545-003
Cy™3 AffiniPure® Goat Anti-Rabbit IgG (H + L) Jackson ImmunoResearch 111-165-003
Chemicals, enzymes, and other reagents
Cardiotoxin CTX Latoxan
Collagenase B Roche Diagnostics GmbH 11088807001
Dispase Roche Diagnostics GmBH 0494207800
FcR Blocking reagent Miltenyi Biotec 130059901
Fluoromount G mounting medium Interchim FP-483331
G/Ultroser PALL Life Sciences #15950017
Hoechst solution Sigma-Aldrich B2261
IFNγ RD systems 485-MI-100
IL10 RD systems 417-ML-005
Matrigel Corning 356231
Ovation SoLo RNA-Seq Library Preparation Kit Nugen/Tecan
Picogreen Thermofisher P7589
Software
FIJI https://imagej.net/
Bcl2FastQ Demux Pipeline (UBP) (software version v2.19.1). Illumina
STAR version 2.6.1 d defaults. Dobin et al, 2013
featureCounts version 1.6.4. Liao et al, 2014
StringTie version 2.0. Pertea et al, 2015
BioMart package. Durinck et al, 2009
ESeq2 Love et al, 2014
ComplexHeatmap package version 2.10.0 make_comb_mat function Gu et al, 2016
PantaRhei package version 0.1.2 sankey diagram function R
fgsea package version 1.16.0 Korotkevich et al, 2021