Table 4.
Metabolic comorbidities and association with severe malaria according to WHO and restricted criteria
| Variable | Malaria severity according to all WHO criteria | Malaria severity using restricted criteria9 | ||||||
|---|---|---|---|---|---|---|---|---|
| Non-severe malaria (N = 169), n (%) | Severe malaria (N = 120) n (%) | Crude OR (95%CI) |
Adjusted OR (95%CI) |
Non-severe malaria (N = 213), n (%) | Severe malaria (N = 76) n (%) |
Crude OR (95%CI) |
Adjusted OR (95%CI) |
|
| Confirmed Diabetes | 10 (5.9) | 26 (21.7) | 4.58 (2.11–9.93) | 3.24 (1.38–7.62)1 | 17 (8.0) | 19 (25.0) | 4.01 (1.95–8.25) | 2.29 (1.02–5.15)3 |
| Metabolic syndrome | 28 (18.5) | 37 (35.9) | 2.60 (1.47–4.60) | 3.18 (1.60–6.37)2 | 41 (20.9) | 27 (35.5) | 2.49 (1.37–4.52) | 2.58 (1.26–5.31)4 |
| Central obesity10 | 50 (30.3) | 45 (39.5) | 1.45 (0.89–2.38) | 1.35 (0.76–2.44)5 | 66 (31.0) | 34 (44.7) | 1.80 (1.05–3.08) | 2.52 (1.24–5.11)6 |
| BMI ≥ 30 kg/m2 | 33 (22.9) | 23 (23.5) | 0.98 (0.54–1.80) | 1.70 (0.91–3.17)7 | 38 (20.2) | 19 (30.2) | 1.70 (0.89–3.25) | 1.46 (0.69–3.09)8 |
1,2adjusted for age group, education, occupation, and HIV status
3,4,5,6,7,8adjusted for age group, education, occupation, and HIV status
9without prostration
10central obesity is defined abnormal waist circumference or BMI ≥ 30 kg/m2