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. 2025 Aug 22;25:1059. doi: 10.1186/s12879-025-11299-2

Table 3.

The association between personal behavior and antibiotic treatment response in children with acute bacterial paranasal sinusitis

Never or seldom Often or very frequently P value
A. Nose blowing N = 14 N = 62
 First line antibiotic use 13 (92.9%) 53 (85.5%) 0.34
 First line antibiotic treatment duration (days) (median, IQR) 14 (8–14) 10 (7–14) 0.08
 Second line antibiotic use 3 (21.4%) 8 (12.9%) 0.35
 Second line antibiotic treatment duration (days) (median, IQR) 14 (7–14) 11.5 (8.5–14) 1.0
 Antibiotic use > 14 days 5 (35.7%) 7 (11.3%) 0.03
B. Nasal irrigation N = 69 N = 7
 First line antibiotic use 61 (88.4%) 6 (85.7%) 0.56
 First line antibiotic treatment duration (days) (median, IQR) 10 (7–14) 12.5 (12–14) 0.19
 Second line antibiotic use 10 (14.5%) 1 (14.3%) 1.0
 Second line antibiotic treatment duration (days) (median, IQR) 11.5 (8–14) 21.0 (21.0) 0.13
 Antibiotic use > 14 days 10 (14.5%) 2 (28.6%) 0.25

First line antibiotic referred to amoxicillin/clavulanate. Second line antibiotics included cefixime, ceftibuten, ciprofloxacin, levofloxacin, and trimethoprim-sulfamethxazole. The regimen was prescribed based on clinical treatment response and nasal discharge culture result