Table 2.
Characteristics of studies reporting the association between IL-10 polymorphisms and the risk of acute coronary syndrome
| IL-10 –592C > A (rs1800872) | ||||||||||||
| First author, publication year | Country | Ethnicity | Cases/controls | Disease type | HWE | NOS score | ||||||
| Biswas, 2014 [42] | India | Asian | 500/500 | STEMI | 0.745 | 7 | ||||||
| Cruz, 2013 [47] | Mexico | Latino | 248/149 | MI | 0.864 | 8 | ||||||
| Donger, 2001 [49] | France | Caucasian | 987/954 | MI | 0.344 | 8 | ||||||
| Fragoso, 2011 [51] | Mexico | Latino | 389/302 | ACS | 0.151 | 8 | ||||||
| Garcia-Garduño, 2024 [53] | Mexico | Latino | 300/300 | ACS | 0.389 | 8 | ||||||
| Koch, 2001 [63] | Germany | Caucasian | 793/340 | MI | 0.977 | 8 | ||||||
| Nasibullin, 2014 [69] | Russia | Caucasian | 225/257 | MI | 0.505 | 8 | ||||||
| Rosner, 2005 [74] | USA | Caucasian | 522/2089 | MI | 0.027 | 8 | ||||||
| Sadikova, 2018 [75] | Russia | Caucasian | 286/301 | MI | 0.218 | 8 | ||||||
| Srikanth Babu, 2012 [77] | India | Asian | 651/432 | ACS | 0.126 | 7 | ||||||
| IL-10 –819C > T (rs1800871) | ||||||||||||
| First author, publication year | Country | Ethnicity | Cases/controls | Disease type | HWE | NOS score | ||||||
| Cruz, 2013 [47] | Mexico | Caucasian | 149/248 | MI | 0.833 | 8 | ||||||
| Donger, 2001 [49] | France | Caucasian | 983/955 | MI | 0.407 | 8 | ||||||
| Fragoso, 2011 [51] | Mexico | Latino | 389/302 | ACS | 0.832 | 8 | ||||||
| Garcia-Garduño, 2024 [53] | Mexico | Latino | 300/300 | ACS | 0.389 | 8 | ||||||
| Koch, 2001 [63] | Germany | Caucasian | 793/340 | MI | 0.977 | 8 | ||||||
| Wang, 2015 [83] | China | Asian | 260/285 | MI | 0.182 | 7 | ||||||
| IL-10 –1082A > G (rs1800896) | ||||||||||||
| First author, publication year | Country | Ethnicity | Cases/controls | Disease type | HWE | NOS score | ||||||
| Aimagambetova, 2016 [36] | Kazakhstan | Asian | 81/100 | STEMI | 0.023 | 7 | ||||||
| Cruz, 2013 [47] | Mexico | Caucasian | 149/248 | MI | 0.833 | 8 | ||||||
| Donger, 2001 [49] | France | Caucasian | 984/952 | MI | 0.943 | 8 | ||||||
| Fragoso, 2011 [51] | Mexico | Latino | 389/302 | ACS | 0.380 | 8 | ||||||
| Garcia-Garduño, 2024 [53] | Mexico | Latino | 300/300 | ACS | 0.409 | 8 | ||||||
| Ianni, 2012 [61] | Italy | Caucasian | 265/239 | AMI | < 0.001 | 7 | ||||||
| Koch, 2001 [63] | Germany | Caucasian | 793/340 | MI | 0.406 | 8 | ||||||
| Lio, 2004 [66] | Italy | Caucasian | 142/153 | AMI | 0.942 | 9 | ||||||
| Lorenzová, 2007 [68] | Czechia | Caucasian | 228/568 | MI | 0.083 | 8 | ||||||
| O'Halloran, 2006 [71] | Ireland | Caucasian | 1598/386 | ACS | 0.001 | 7 | ||||||
| Srikanth Babu, 2012 [77] | India | Asian | 651/432 | ACS | 0.079 | 7 | ||||||
| Wang, 2015 [83] | China | Asian | 260/285 | MI | 0.110 | 7 | ||||||
The bold number means statistically significant datum (p < 0.05)
IL Interleukin, AMI Acute myocardial infarction, MI Myocardial infarction, ACS Acute coronary syndrome, UA Unstable angina, STEMI ST elevation myocardial infarction, HWE Hardy–Weinberg equilibrium (with a p-value for the control group)