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. 2025 Aug 22;23:262. doi: 10.1186/s12915-025-02321-9

Table 1.

Acid production of S. wiggsiae biofilm

Time (h) pH of spent medium at the end of each time points
Control Sucrose* Glucose Xylitol* Rubusoside Rubusoside + Sucrose
48h 5.08 ± 0.03b 4.52 ± 0.05a 4.48 ± 0.03a 4.82 ± 0.29c 6.55 ± 0.01d 6.48 ± 0.02d
72h 4.58 ± 0.02b 4.08 ± 0.04a 4.09 ± 0.15a 4.55 ± 0.09b 6.45 ± 0.07c 6.48 ± 0.04c
96h 4.39 ± 0.02b 4.06 ± 0.03a 4.08 ± 0.02a 4.39 ± 0.02b 6.44 ± 0.03c 6.34 ± 0.05c
120h 4.37 ± 0.02b 4.05 ± 0.06a 4.03 ± 0.03a 4.38 ± 0.02b 6.39 ± 0.07c 6.32 ± 0.07d
144h 4.34 ± 0.02b 3.96 ± 0.02a 3.92 ± 0.02a 4.36 ± 0.03b 6.31± 0.06c 6.22 ± 0.05c

*, P < 0.05, indicates that the pH of this group changes statistically over time