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. 2025 Aug 23;25:1364. doi: 10.1186/s12885-025-14684-x

Table 1.

Baseline clinical characteristics

Characteristics DWI-Guided DP-IMRT Number of patients (%) Conventional MRI-based IMRT Number of patients (%) P value
Total 126 134
Age, y 0.412
Median 57 56
Range 31–75 31–75
Sex 0.166
Male 115 (91.3) 130 (97)
Female 11 (8.7) 4 (3)
Karnofsky Scale 0.502
90–100 123 (97.6) 128 (95.5)
70–80 3 (2.4) 6 (4.5)
Disease Primary Site 0.086
Oral Cavity 18 (14.3) 16 (11.9)
Oropharynx 48 (38.1) 37 (27.6)
Larynx 3 (2.4) 10 (7.5)
Hypopharynx 57 (45.2) 71 (53.0)
Disease State 0.832
III 21 (16.7) 20 (14.9)
IV 105 (83.3) 114 (85.1)
T Stage 0.652
T1 10 (7.9) 9 (6.7)
T2 37 (29.4) 48 (35.9)
T3 24 (19.0) 20 (14.9)
T4 55 (43.7) 57 (42.5)
N Stage 0.918
N0 6 (4.8) 8 (5.9)
N1 25 (19.8) 23 (17.2)
N2 80 (63.5) 88 (65.7)
N3 15 (11.9) 15 (11.2)
p16 0.137
Positive 13 (10.3) 8 (6.0)
Negative 113 (89.7) 126 (94.0)
Immunotherapy 35 (27.8) 24 (14.3)