Table 4.

Genotype and allele frequencies of gene variants analyzed concerning high or low count of platelets and mean platelet volume

	Genotype			χ2	p	Alleles		χ2	p
Platelet count IL10
rs1554286	GG	GA	AA			G	A
Low	38 (0.28)	69 (0.51)	28 (0.21)	0	1	145 (0.54)	125 (0.46)	0.01	0.96
High	28 (0.28)	51 (0.51)	21 (0.21)			107 (0.54)	93 (0.46)
TNF
rs1800629	GG	GA	AA			G	A
Low	129 (0.96)	6 (0.04)	0	1.3	0.25	264 (0.98)	6 (0.02)	8.6	0.003
High	92 (0.92)	8 (0.08)	0			184 (0.92)	16 (0.08)
TLR2
rs7656411	TT	TG	GG			T	G
Low	86 (0.64)	43 (0.32)	6 (0.04)	1.0	0.58	215 (0.8)	55 (0.2)	0.4	0.52
High	66 (0.66)	32 (0.32)	2 (0.02)			164 (0.82)	36 (0.18)
TLR6
rs5743827	CC	CT	TT			C	T
Low	105 (0.78)	26 (0.19)	4 (0.03)	0.02	0.98	236 (0.87)	34 (0.13)	0.01	0.89
High	77 (0.77)	20 (0.20)	3 (0.03)			174 (0.87)	26 (0.13)
MPV
IL10
rs1554286	GG	GA	AA			G	A
Low	29 (0.35)	41 (0.49)	13 (0.16)	3.8	0.23	99 (0.6)	67 (0.4)	3.7	0.054
High	36 (0.24)	76 (0.52)	35 (0.24)			148 (0.5)	146 (0.5)
TNF
rs1800629	GG	GA	AA			G	A
Low	80 (0.96)	3 (0.04)	-	0.79	0.37	163 (0.98)	3 (0.02)	1.3	0.24
High	136 (0.93)	11(0.07)	-			283 (0.96)	11 (0.04)
TLR2
rs7656411	TT	TG	GG			T	G
Low	49 (0.59)	30 (0.36)	4 (0.05)	2.4	0.29	128 (0.77)	38 (0.23)	2.1	0.14
High	99 (0.67)	45 (0.31)	3 (0.02)			243 (0.83)	51 (0.17)
TLR6
rs5743827	CC	CT	TT			C	T
Low	64 (0.77)	17 (0.2)	2 (0.03)	0.2	0.91	145 (0.87)	21 (0.13)	0.03	0.85
High	113 (0.77)	29 (0.2)	5 (0.03)			255 (0.87)	39 (0.13)

MPV Mean platelet volume

Bolded text indicates a p-value below 0.0125 (4 SNPs/0.05)