Table 5.
Gene–gene interaction model for platelet count and MPV in patients with schizophrenia
| Models | TA | CVC | OR (95% IC) | p |
|---|---|---|---|---|
| MPV | ||||
| IL-10, TLR2 | 0.579 | 10/10 | 2.12 (1.22–3.55) | ns |
| IL-10, TLR2, TLR6 | 0.523 | 7/10 | 2.34 (1.35–4.05) | ns |
| IL-10, TNF, TLR2, TLR6 | 0.503 | 10/10 | 2.61 (1.48–4.61) | ns |
| Platelet count | ||||
| TLR2, TLR6 | 0.432 | 6/10 | 1.52 (0.88–2.62) | ns |
| IL-10, TLR2, TLR6 | 0.504 | 9/10 | 2.09 (1.21–3.6) | ns |
| IL-10, TNF, TLR2, TLR6 | 0.505 | 10/10 | 1.05 (0.18–5.96) | ns |
IL-10: rs1554286. TNF: rs1800629. TLR2: rs7656411. TLR6: rs5743827
TA Test accuracy, CVC cross-validation consistency
1000-fold permutation. ns not statistically significant