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. 2025 Aug 23;25:655. doi: 10.1186/s12877-025-06280-2

Table 2.

Logistic regression analysis assessing the association of frailty and frailty domains with syncope and its subtypes

FRAILTY SYNCOPE OR 95% CI p
fr-AGILEa Overall 1.468 1.276–1.690 0.001
Cardiogenic 1.034 0.786–1.358 0.813
Reflex 1.463 1.190–1.797 0.001
Orthostatic 1.283 1.001–1.644 0.049
Unknown 1.844 1.331–2.558 0.001
Frailty domainsb Overall OR 95% CI p
Physical 1.802 1.322–2.456 0.001
Mental 1.576 1.181–2.102 0.002
Nutritional 2.178 1.566–3.028 0.001
Social 1.569 1.012–2.431 0.044

Bold emphasis inside table indicate the statistical significance

OR Odds Ratio, CI Confidence Interval

Legend: a multivariate analysis, adjusted for age, sex, comorbidities, and number of medications, showing the association between fr-AGILE score and the incidence of overall and distinct types of syncope

bmultivariate analysis, adjusted for age, sex, comorbidities, and number of medications, assessing the association between each domain of multidimensional frailty and syncope