Fig. 2.

Correlation of bacterial abundance with prognostic indicators and ileal endoscopic findings in pediatric Crohn’s disease (CD). A Patients were categorized into three groups: Control (Ctrl), CD without relapse, and CD with relapse. Within each group, individuals were arranged by increasing bacterial read count. The blue bars (left y-axis) show the average bacterial read count, normalized to counts per million mapped reads (CPM) for each patient. The orange bars (right y-axis) represent the time to relapse (in months) for patients with CD who experienced relapse. The red line indicates the Rutgeerts score, which assesses the severity of endoscopic findings in CD (ranging from i0 [no lesions] to i4 [diffuse inflammation with large ulcers]). Error bars represent the standard error of the mean. B Endoscopic images of the terminal ileum in patients with CD are presented, corresponding to the order of patients in panel A