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. 2025 Aug 22;25:165. doi: 10.1186/s12873-025-01327-4

Table 5.

Sensitivity, specificity, negative predictive value (NPV), positive predictive value (PPV), negative likelihood ratio (NLR), positive likelihood ratio (PLR) of key cut-offs for each stratification tool

Stratification tool Cut-off Sensitivity (%) Specificity (%) NPV (%) PPV (%) PLR NLR
HEART ≤ 3 97.1 51.9 98.18 39.98 2.01 0.05
≤ 4 86.8 78.2 94.72 56.79 3.98 0.16
HET ≤ 1 92.6 52.9 95.58 39.35 1.96 0.13
≤ 2 80.9 91.7 93.56 76.28 9.74 0.20
TIMI ≤ 1 98.5 26.7 98.17 30.72 1.34 0.05
≤ 2 92.6 63.1 96.27 45.30 2.50 0.11
GRACE ≤ 91 91.9 55.4 95.3 40.4 2.060 0.14
EDACS-ADP = low Risk 91.2 69.4 95.98 49.59 2.98 0.12